The MARGE Career Development and Training Program is divided into two parts. The overriding objective of the first part, the Individual Career Development Support Program, is to bring a cadre of bright, motivated, young scientists into the broad area of biodefense and emerging infectious diseases research. Two Career Development Awards be offered in the amount of $150,000 per year for two years of supervised study and research for professionals who have the potential to develop into productive scientific investigators. This Program will enhance and support the MARCE Strategic Plan in several ways. First, the addition of new investigators will complement the existing interactions between established MARCE investigators and inject fresh ideas into the field. Second, the addition of the recipients'projects will further expand the research portfolio. Third, Career Development projects will enhance synergies with the existing Research Programs through ties to the sub-themes of those Programs. For the second part of this Program, the MARCE will offer the following Group Career Development Activities based on a needs assessment and the success of these training courses in the first funding period: 1) BSL-3 Laboratory Biosafety Training. This three-day course offered at the U. of Maryland will feature lectures, group learning activities, demonstrations, and hands-on training for BSL-3 experiments and aerobiology;2) Media Training for Bio Scientists in Preparation for Public Health Emergencies. This one day-course offered by the George Washington U. will prepare scientists to become effective subject matter communicators during public health emergencies;3) Training in Good Manufacturing Practices, Good Laboratory Practices and Process Development. This two-day course at the Sanofi Pasteur Vaccines manufacturing facilities will cover GMP, GLP, process development, regulatory issues and manufacture;and 4) Training in the Complexity of Response to Biological Emergencies. The U. of Maryland Center for Health and Homeland Security will host an interactive two-day workshop where national and international experts discuss how they will prepare for and respond to a bioterrorist attack or emerging infectious disease outbreak. In addition, a Clinical Issues Training Committee, staffed by infectious disease experts at the major MARCE institutions, will be prepared to rapidly offer instruction on emerging infections or biodefense issues in the face of an event. Together, the Career and Training Programs will increase the overall pool of trained investigators and qualified researchers in this field.
The Career Development Program will bring a cadre of new, bright, motivated scientists into the broad area of biodefense and infectious disease research. Together with the Group Training component, this Program will increase the overall pool of trained investigators and qualified researchers in this field working ultimately towards therapeutic, preventive, or diagnostic products for the benefit of public health.
|Champion, Anna E; Bandara, Aloka B; Mohapatra, Nrusingh et al. (2018) Further Characterization of the Capsule-Like Complex (CLC) Produced by Francisella tularensis Subspecies tularensis: Protective Efficacy and Similarity to Outer Membrane Vesicles. Front Cell Infect Microbiol 8:182|
|Bridge, Dacie R; Blum, Faith C; Jang, Sungil et al. (2017) Creation and Initial Characterization of Isogenic Helicobacter pylori CagA EPIYA Variants Reveals Differential Activation of Host Cell Signaling Pathways. Sci Rep 7:11057|
|Kaempfer, Raymond; Popugailo, Andrey; Levy, Revital et al. (2017) Bacterial superantigen toxins induce a lethal cytokine storm by enhancing B7-2/CD28 costimulatory receptor engagement, a critical immune checkpoint. Receptors Clin Investig 4:|
|Molleston, Jerome M; Cherry, Sara (2017) Attacked from All Sides: RNA Decay in Antiviral Defense. Viruses 9:|
|Cifuentes-Muñoz, Nicolás; Sun, Weina; Ray, Greeshma et al. (2017) Mutations in the Transmembrane Domain and Cytoplasmic Tail of Hendra Virus Fusion Protein Disrupt Virus-Like-Particle Assembly. J Virol 91:|
|Sarute, Nicolás; Ross, Susan R (2017) New World Arenavirus Biology. Annu Rev Virol 4:141-158|
|Ramachandran, Girish; Aheto, Komi; Shirtliff, Mark E et al. (2016) Poor biofilm-forming ability and long-term survival of invasive Salmonella Typhimurium ST313. Pathog Dis 74:|
|Wahid, Rezwanul; Fresnay, Stephanie; Levine, Myron M et al. (2016) Cross-reactive multifunctional CD4+ T cell responses against Salmonella enterica serovars Typhi, Paratyphi A and Paratyphi B in humans following immunization with live oral typhoid vaccine Ty21a. Clin Immunol 173:87-95|
|Li, Huiguang; Hwang, Young; Perry, Kay et al. (2016) Structure and Metal Binding Properties of a Poxvirus Resolvase. J Biol Chem 291:11094-104|
|Chou, Yi-Ying; Cuevas, Christian; Carocci, Margot et al. (2016) Identification and Characterization of a Novel Broad-Spectrum Virus Entry Inhibitor. J Virol 90:4494-4510|
Showing the most recent 10 out of 375 publications