The CD 1 Individual Career Development Support (ICDS) Program will provide individualized training that is focused on advanced post-doctoral and professional degree scientists, junior or senior faculty, or other health professionals who seek career opportunities in biodefense and emerging diseases research. All Individual Trainees will also be encouraged to take part in the Group Training activities (CD 2.1 Group Product Development Training and CD 2.2 Group Biosafety Level 3 Training), and certain Individual Trainees might even decide to focus their research on Product Development or Biosafety. The research projects will exploit the extraordinary expertise and facilities available in Region VIII concerning research on bacterial and viral Category A -C priority pathogens or emerging pathogens, and they will integrate with, complement, and enhance the overall mission of the RMRCE. The goals of this program will be achieved through the following Specific Aims: * To identify and recruit the """"""""best and brightest"""""""" scientists and health professionals. * To assist recruits, when needed, in identifying mentors who can provide the expertise and resources for the desired training in biodefense or EID research (including basic and translational research, product development and biosafety). ? To assist Mentors by identifying and providing resources that can aid the trainees in developing their careers (e.g., information on NIH workshops and trainee-appropriate funding opportunities). * To conduct Outcomes Assessment through semi-annual reports and annual reports, and to track the careers of ICDS program """"""""alumni"""""""" through agreed-upon modes of contact (e.g., e-mail, phone, letter). * To continuously monitor the progress of trainees and the success of the trainee/mentor relationship by maintaining regular, informal communication with both the trainee and the mentor. The Individual Career Development Support Program directly supports the RMRCE's objective of providing trained personnel for biodefense and emerging infectious diseases research. Most if not all of the trainees will work in the laboratories of RMRCE-funded Pis, and will thus contribute to the successful attainment of research project goals. The working relationship between each trainee and the projects/cores of the RMRCE will depend on the Mentor and the aims of the Trainee's research project.
The CD 1 Individual Career Development Support Program of the RMRCE will address the NIH objective of training a sufficient number of scientists and health professionals with expertise in biodefense and emerging infectious diseases research. These types of researchers will contribute to the discovery and development of vaccines, detection tests, antibiotics and drugs to treat disease outbreaks of public health importance, regardless of whether such outbreaks are intentional or naturally-occurring.
|Lehman, Stephanie S; Mladinich, Katherine M; Boonyakanog, Angkana et al. (2016) Versatile nourseothricin and streptomycin/spectinomycin resistance gene cassettes and their use in chromosome integration vectors. J Microbiol Methods 129:8-13|
|Knudson, Susan E; Cummings, Jason E; Bommineni, Gopal R et al. (2016) Formulation studies of InhA inhibitors and combination therapy to improve efficacy against Mycobacterium tuberculosis. Tuberculosis (Edinb) 101:8-14|
|Charley, Phillida A; Wilusz, Jeffrey (2016) Standing your ground to exoribonucleases: Function of Flavivirus long non-coding RNAs. Virus Res 212:70-7|
|Phillips, Aaron T; Rico, Amber B; Stauft, Charles B et al. (2016) Entry Sites of Venezuelan and Western Equine Encephalitis Viruses in the Mouse Central Nervous System following Peripheral Infection. J Virol 90:5785-96|
|Westover, Jonna B; Sefing, Eric J; Bailey, Kevin W et al. (2016) Low-dose ribavirin potentiates the antiviral activity of favipiravir against hemorrhagic fever viruses. Antiviral Res 126:62-8|
|Shankar, Sundaresh; Whitby, Landon R; Casquilho-Gray, Hedi E et al. (2016) Small-Molecule Fusion Inhibitors Bind the pH-Sensing Stable Signal Peptide-GP2 Subunit Interface of the Lassa Virus Envelope Glycoprotein. J Virol 90:6799-807|
|York, Joanne; Nunberg, Jack H (2016) Myristoylation of the Arenavirus Envelope Glycoprotein Stable Signal Peptide Is Critical for Membrane Fusion but Dispensable for Virion Morphogenesis. J Virol 90:8341-50|
|Rhodes, Katherine A; Schweizer, Herbert P (2016) Antibiotic resistance in Burkholderia species. Drug Resist Updat 28:82-90|
|Voge, Natalia V; Perera, Rushika; Mahapatra, Sebabrata et al. (2016) Metabolomics-Based Discovery of Small Molecule Biomarkers in Serum Associated with Dengue Virus Infections and Disease Outcomes. PLoS Negl Trop Dis 10:e0004449|
|Rico, Amber B; Phillips, Aaron T; Schountz, Tony et al. (2016) Venezuelan and western equine encephalitis virus E1 liposome antigen nucleic acid complexes protect mice from lethal challenge with multiple alphaviruses. Virology 499:30-39|
Showing the most recent 10 out of 244 publications