The purpose of the Training and Career Development Program of the Primary Immune Deficiency Treatment Consortium (PIDTC) is to provide career development that will enhance education at the clinical postdoctoral level. By training clinical and translational investigators specifically in the area of primary immune deficiency (PID), the cadre of physicians and scientists involved in elucidating the pathogenesis of these disorders and in developing and applying improved therapies will be augmented. Clinical investigators caring for patients with PID require a complex set of skills, including knowledge of the biology of immune reconstitution and transplant immunology, familiarity with diagnosis and medical management of patients with PID, and expertise in hematology, infectious diseases, genetics and critical care of ill patients undergoing hematopoietic cell transplantation. The PIDTC brings together specialists from across the US and Canada and with its research activities provides a unique platform to train new investigators in the course of disseminating knowledge to providers, patients and families. The goal of PIDTC training grants is to provide support for research at the level of the clinical post-doctoral fellow. This career development support will enrich the pool of talented clinicians caring for patients with PID and advance translational research in the field.

Public Health Relevance

Primary immune deficiencies (PIDs) are rare, life-threatening inherited defects in the immune system. The Training and Career Development portion of the Primary Immune Deficiency Treatment Consortium (PIDTC)'s will help to achieve one of the major objectives of the PIDTC by promoting research by young investigators of the causes and treatment of the primary immune deficiencies so that there will be a continuum of expertise throughout North America in this field

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Specialized Center--Cooperative Agreements (U54)
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Special Emphasis Panel (ZRG1-HOP-Y)
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University of California San Francisco
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Griffith, Linda M; Cowan, Morton J; Notarangelo, Luigi D et al. (2014) Primary Immune Deficiency Treatment Consortium (PIDTC) report. J Allergy Clin Immunol 133:335-47
Medical Advisory Committee of the Immune Deficiency Foundation; Shearer, William T; Fleisher, Thomas A et al. (2014) Recommendations for live viral and bacterial vaccines in immunodeficient patients and their close contacts. J Allergy Clin Immunol 133:961-6
Chinen, Javier; Notarangelo, Luigi D; Shearer, William T (2014) Advances in basic and clinical immunology in 2013. J Allergy Clin Immunol 133:967-76
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