Training new investigators is a core mission of the Vasculitis Clinical Research Consortium (VCRC) and of high-priority to the Vasculitis Foundation (VF). The VCRC-VF Fellowship Program has been extremely successful. During the two initial 5-year grant periods, the VCRC recruited and provided salary support for 9 VCRC Fellows for two-year structured fellowships, all of whom remain in academic medicine, are specifically focused on caring for patients with vasculitis, and are engaged in clinical research in vasculitis. The VCRC-VF Fellowship is a structured, mentored training program of up to two years for physician-investigators who have developed an interest in vasculitis and wish to pursue a period of specialized training with an emphasis on translational and patient-oriented clinical investigation. The trainee undertakes the fellowship at one of the VCRC clinical research sites. Fellows who have developed an interest in vasculitis are recruited from Rheumatology, Nephrology, Pulmonology, Neurology, Vascular Medicine/Cardiology or other subspecialties. The Fellowship involves conduct of hypothesis-based clinical research in vasculitis, limited clinical experience focused on care of patients with vasculitis, and coursework directed at acquiring advanced skills in clinical research methodology. We propose to maintain the same careful approach to applicant selection and comprehensive training we have refined in the past decade, but will expand the number of Fellows and the number of VCRC Centers eligible to host VCRC Fellows. The VCRC-VF Fellowship will have additional generous financial support from the VF. The VCRC-VF Fellowship addresses the need to train more physicians in the care of patients with vasculitis and to develop a new generation of vasculitis clinical investigators.

Public Health Relevance

The VCRC-VF Fellowship provides support for a 2-year program to train physicians in the care of patients with vasculitis and to provide the Fellows with additional advanced training in clinical research in vasculitis. This program will be a combine effort of the Vasculitis Clinical Research Consortium and the Vasculitis Foundation.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
2U54AR057319-12
Application #
8918193
Study Section
Special Emphasis Panel (ZTR1-CI-8 (01))
Program Officer
Wang, Yan Z
Project Start
2014-09-01
Project End
2019-08-31
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
12
Fiscal Year
2014
Total Cost
$118,240
Indirect Cost
$37,801
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Hatemi, Gulen; Merkel, Peter A; Hamuryudan, Vedat et al. (2014) Outcome measures used in clinical trials for Beh├žet syndrome: a systematic review. J Rheumatol 41:599-612
Monach, Paul A (2014) Biomarkers in vasculitis. Curr Opin Rheumatol 26:24-30
Grayson, Peter C; Amudala, Naomi A; McAlear, Carol A et al. (2014) Causal attributions about disease onset and relapse in patients with systemic vasculitis. J Rheumatol 41:923-30
Merkel, Peter A; Aydin, Sibel Z; Boers, Maarten et al. (2014) Current status of outcome measure development in vasculitis. J Rheumatol 41:593-8
Mooney, Janice; Spalding, Nicola; Poland, Fiona et al. (2014) The informational needs of patients with ANCA-associated vasculitis-development of an informational needs questionnaire. Rheumatology (Oxford) 53:1414-21
Langford, Carol A; Monach, Paul A; Specks, Ulrich et al. (2014) An open-label trial of abatacept (CTLA4-IG) in non-severe relapsing granulomatosis with polyangiitis (Wegener's). Ann Rheum Dis 73:1376-9
Kermani, Tanaz A; Warrington, Kenneth J; Crowson, Cynthia S et al. (2013) Large-vessel involvement in giant cell arteritis: a population-based cohort study of the incidence-trends and prognosis. Ann Rheum Dis 72:1989-94
Monach, Paul A; Warner, Roscoe L; Tomasson, Gunnar et al. (2013) Serum proteins reflecting inflammation, injury and repair as biomarkers of disease activity in ANCA-associated vasculitis. Ann Rheum Dis 72:1342-50
Schmidt, Jean; Kermani, Tanaz A; Bacani, A Kirstin et al. (2013) Diagnostic features, treatment, and outcomes of Takayasu arteritis in a US cohort of 126 patients. Mayo Clin Proc 88:822-30
Grayson, Peter C; Amudala, Naomi A; Mcalear, Carol A et al. (2013) Illness perceptions and fatigue in systemic vasculitis. Arthritis Care Res (Hoboken) 65:1835-43

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