Early recruitment of underrepresented minorities from underserved communities into biomedical and health research training and education is essential to ensure that society's diversity is reflected in those professions. Given the critical cancer health disparities faced in Hispanic populations, in this 2""""""""""""""""^ competitive renewal of the Training Program between UPR and MDACC we will continue to develop a comprehensive pipeline of trainees from undergraduates to postgraduates to increase the number of Hispanic clinicians, scientists, physician scientists and health professionals knowledgeable and committed to careers in cancer research and medicine, as well as foster a faculty career development and mentoring program for junior faculty and for senior faculty transitioning to careers in cancer research. The UPR and MDACC Co-leaders have designed the training program to focus on several key areas including biomedical, clinical and translational research. Training methodology will include didactics, research experiences, enrichment opportunities, an MD/PhD program, postgraduate biomedical and clinical training, and training in cancer prevention and health disparities. The training program will be supplemented and enhanced by a new Cancer Education Core which offers a core curriculum in cancer and didactics in cancer health disparities. This separate core will develop a curriculum in cancer that will be integrated into the training program. Career development will enhance existing programs to build both academic skills such as grant writing, publishing in high impact peer-reviewed journals, and giving effective presentations, as well as professional skills in negotiating and effective communication. Senior faculty transitioning to a career in cancer research and medicine will participate in the career development program. The Training and Career Development Core (TCDC) will collaborate with the planning evaluation core to use outcomes-based logic modeling to evaluate qualitative and quantitative data so as to measure impact of the programs. Qualitative surveys will be utilized to obtain feedback from trainees and junior faculty on their immediate and long-term needs and interests, as well as to rate their experiences participating in various programs. A clear plan will be developed and implemented to enable the UPRCCC to independently sustain outstanding training and career development programs in cancer medicine and research. The TCDC, along with the new Education Core (Section E,2), functions as an integrated training, career development, and education program to fill a knowledge gap and foster a bridge to success for the next generation of Hispanic cancer researchers and physicians.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA096297-12
Application #
8754452
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
12
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Puerto Rico Med Sciences
Department
Type
DUNS #
City
San Juan
State
PR
Country
United States
Zip Code
00936
Villar-Prados, Alejandro; Wu, Sherry Y; Court, Karem A et al. (2018) Predicting novel therapies and targets: Regulation of Notch3 by the bromodomain protein BRD4. Mol Cancer Ther :
Allen, Julie K; Armaiz-Pena, Guillermo N; Nagaraja, Archana S et al. (2018) Sustained Adrenergic Signaling Promotes Intratumoral Innervation through BDNF Induction. Cancer Res 78:3233-3242
Marqués-Lespier, Juan M; Soto-Salgado, Marievelisse; González-Pons, María et al. (2018) Prevalence of Synchronous Oligopolyposis in Incident Colorectal Cancer: A Population-Based Study. P R Health Sci J 37:39-45
Maldonado, María Del Mar; Dharmawardhane, Suranganie (2018) Targeting Rac and Cdc42 GTPases in Cancer. Cancer Res 78:3101-3111
González-Pons, María; Soto-Salgado, Marievelisse; Sevilla, Javier et al. (2018) Seroprevalence of Helicobacter pylori in Hispanics living in Puerto Rico: A population-based study. Helicobacter 23:
Monroig-Bosque, Paloma Del C; Shah, Maitri Y; Fu, Xiao et al. (2018) OncomiR-10b hijacks the small molecule inhibitor linifanib in human cancers. Sci Rep 8:13106
Das, Soma; Parga, Kenia; Chakraborty, Indranil et al. (2018) Magnetic resonance imaging contrast enhancement in vitro and in vivo by octanuclear iron-oxo cluster-based agents. J Inorg Biochem 186:176-186
Thapa, Bibek; Diaz-Diestra, Daysi; Santiago-Medina, Carlene et al. (2018) T1- and T2-weighted Magnetic Resonance Dual Contrast by Single Core Truncated Cubic Iron Oxide Nanoparticles with Abrupt Cellular Internalization and Immune Evasion. ACS Appl Bio Mater 1:79-89
Gonzalez, Velda J; McMillan, Susan; Pedro, Elsa et al. (2018) The Health related Quality of Life of Puerto Ricans during Cancer Treatments; A Pilot Study. P R Health Sci J 37:46-51
Gonzalez, Velda J; Abbas-Aghababazadeh, Farnoosh; Fridley, Brooke L et al. (2018) Expression of Sestrin Genes in Radiotherapy for Prostate Cancer and Its Association With Fatigue: A Proof-of-Concept Study. Biol Res Nurs 20:218-226

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