This application is for the continuation of the existing Partnership beWveen Morehouse School of Medicine (MSM), Tuskegee University (TU), and the UAB Comprehensive Cancer Center (UABCCC). The Partnership, located in the heart ofthe Southeast, a region with a large, historically underserved African American population, has goals of attaining excellence in research focused on the basis of cancer health disparities and on reducing the cancer burden. All three institutions, w/hich are assisting underserved communities, possess unique strengths that supplement each other. The primary objectives are to maintain progress in establishing productive cancer research programs at MSM and TU and to persist in developing a pipeline of prospective minority investigators at TU. The Partnership has three Cores (Administrative, Planning &Evaluation, and Developmental). Within the Developmental Core, there are four Research Programs and two Shared Resources (Bioethics and Biostatistics). With the Research Programs, the Partnership will continue: 1) to tap the pool of talented students and faculty at MSM and TU through the Research Training and Career Development (RTCD) Program, linking them to established Investigators and to the research infrastructure at the UABCCC;2) to promote a Developmental Research (DR) Program, which provides funding for research projects;3) to encourage graduate and undergraduate students across various scientific disciplines to pursue careers in the biosciences through our Cancer Education Program and to provide a pipeline into our RTCD and DR Programs;and 4) to promote cancer awareness and healthy lifestyles among our underserved populations and increase minority participation in therapeutic clinical trails our established Community Outreach Program. The Bioethics Shared Resource promotes and ensures adherence to bioethical principles and addresses ethical considerations in relationships among our institutions and between institutions and communities. The Biostatistics Shared Resource maintains statistical support to all programs. The Partnership will continue to demonstrate its enhanced capability to conduct research on cancer health disparities.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA118623-08
Application #
8550770
Study Section
Special Emphasis Panel (ZCA1-SRLB-Y (O1))
Program Officer
Ogunbiyi, Peter
Project Start
2005-09-28
Project End
2016-08-31
Budget Start
2013-09-01
Budget End
2014-08-31
Support Year
8
Fiscal Year
2013
Total Cost
$655,170
Indirect Cost
$352,657
Name
Tuskegee University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
128214178
City
Tuskegee
State
AL
Country
United States
Zip Code
36088
Akintobi, Tabia Henry; Lockamy, Elise; Goodin, Lisa et al. (2018) Processes and Outcomes of a Community-Based Participatory Research-Driven Health Needs Assessment: A Tool for Moving Health Disparity Reporting to Evidence-Based Action. Prog Community Health Partnersh 12:139-147
Angajala, Anusha; Mothershed, Essynce; Davis, Melissa B et al. (2018) Quadruple Negative Breast Cancers (QNBC) Demonstrate Subtype Consistency among Primary and Recurrent or Metastatic Breast Cancer. Transl Oncol 12:493-501
Davis, Melissa; Tripathi, Shweta; Hughley, Raymond et al. (2018) AR negative triple negative or ""quadruple negative"" breast cancers in African American women have an enriched basal and immune signature. PLoS One 13:e0196909
Angajala, Anusha; Lim, Sangbin; Phillips, Joshua B et al. (2018) Diverse Roles of Mitochondria in Immune Responses: Novel Insights Into Immuno-Metabolism. Front Immunol 9:1605
Abisoye-Ogunniyan, Abisola; Lin, Huxian; Ghebremedhin, Anghesom et al. (2018) Transcriptional repressor Kaiso promotes epithelial to mesenchymal transition and metastasis in prostate cancer through direct regulation of miR-200c. Cancer Lett 431:1-10
Mukherjee, Angana; Hollern, Daniel P; Williams, Oluwasina G et al. (2018) A Review of FOXI3 Regulation of Development and Possible Roles in Cancer Progression and Metastasis. Front Cell Dev Biol 6:69
Sodeke, Stephen O; Wilson, Wylin D (2017) Integrative Bioethics is a Bridge-Builder Worth Considering to Get Desired Results. Am J Bioeth 17:30-32
Narla, Deepti; Slagle, Stacey B; Schaefer, Caitlin M et al. (2017) Loss of peri-Wolffian duct stromal Frs2? expression in mice leads to abnormal ureteric bud induction and vesicoureteral reflux. Pediatr Res 82:1022-1029
Afolabi, Michael O S; Sodeke, Stephen O (2017) Reconciling Competence and Consent in Opioid-Dependence Research: The Value of Vulnerability Rhetoric. Am J Bioeth 17:48-50
Yoo, Wonsuk; Kim, Sangmi; Huh, Warner K et al. (2017) Recent trends in racial and regional disparities in cervical cancer incidence and mortality in United States. PLoS One 12:e0172548

Showing the most recent 10 out of 141 publications