This application is for continuation of the existing partnership between Morehouse School of Medicine (MSM), Tuskegee University (TU), and the University of Alabama at Birmingham (UAB) Comprehensive Cancer Center (UABCCC). The three institutions, each serving a community with major black-white racial disparities, possess unique sets of strengths that complement each other. The primary objectives are to maintain progress in establishment of effective cancer research programs at MSM and TU and to persist In developing a pipeline of prospective minority Investigators at TU. The Partnership, with four effective Research Programs In education, research, career progression, and cancer outreach, will continue: 1) to tap the pool of talented students and faculty currently at MSM and TU through an effective Research Training and Career Development (RTCD) Program, linking them to established investigators and to the research Infrastructure at the UABCCC;2) to promote a Developmental Research Program, which provides funding opportunities to conduct research projects in parallel to the RTCD Program;3) to encourage postdoctoral fellows, graduate students, and undergraduates across scientific disciplines to pursue careers in the biosciences through our Cancer Education Program and to provide a pipeline into our RTCD and Developmental Research Programs;and, 4) through our established Community Outreach (now Cancer Outreach) Program, to promote cancer screening and healthy lifestyles among our most underserved populations and increase minority participation in therapeutic clinical trials. The partnership has two Interactive Shared Resources: 1) The Bioethics Shared Resource promotes and ensures adherence to bioethical principles and addresses ethical considerations in relationships between majority and minority institutions and between institutions and underserved communities;and 2) The Biostatistics Shared Resource maintains statistical support to all programs ofthe Partnership. With continued accomplishments, this partnership will provide the UABCCC, MSM, and TU with an enhanced capability to conduct research on cancer health disparities.

Public Health Relevance

This project will address the disparity in cancer incidence and mortality between African Americans and other racial/ethnic groups. It will help to build cancer research programs at two historically black Institutions of higher education -- Morehouse School of Medicine and Tuskegee University - and will encourage research on cancer disparities at one of the country's leading Comprehensive Cancer Centers, the University of Alabama at Birmingham CCC

National Institute of Health (NIH)
National Cancer Institute (NCI)
Specialized Center--Cooperative Agreements (U54)
Project #
Application #
Study Section
Special Emphasis Panel (ZCA1-SRLB-Y (O1))
Program Officer
Ogunbiyi, Peter
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Morehouse School of Medicine
Public Health & Prev Medicine
Schools of Medicine
United States
Zip Code
Mullen, McKay; Gonzalez-Perez, Ruben Rene (2016) Leptin-Induced JAK/STAT Signaling and Cancer Growth. Vaccines (Basel) 4:
Kapur, Neeraj; Mir, Hina; Clark Iii, Clarence E et al. (2016) CCR6 expression in colon cancer is associated with advanced disease and supports epithelial-to-mesenchymal transition. Br J Cancer 114:1343-51
Zhang, Wei; Yi, Bin; Wang, Chao et al. (2016) Silencing of CD24 Enhances the PRIMA-1-Induced Restoration of Mutant p53 in Prostate Cancer Cells. Clin Cancer Res 22:2545-54
Chowdhury, Indrajit; Thomas, Kelwyn; Thompson, Winston E (2016) Prohibitin( PHB) roles in granulosa cell physiology. Cell Tissue Res 363:19-29
Kaur, Punit; Aliru, Maureen L; Chadha, Awalpreet S et al. (2016) Hyperthermia using nanoparticles--Promises and pitfalls. Int J Hyperthermia 32:76-88
Lipsey, Crystal C; Harbuzariu, Adriana; Daley-Brown, Danielle et al. (2016) Oncogenic role of leptin and Notch interleukin-1 leptin crosstalk outcome in cancer. World J Methodol 6:43-55
Holden, Kisha; Charles, Lisa; King, Stephen et al. (2015) Reducing Health Disparities and Improving Health Equity in Saint Lucia. Int J Environ Res Public Health 13:ijerph13010037
McGregor, Brian; Mack, Dominic; Wrenn, Glenda et al. (2015) Improving Service Coordination and Reducing Mental Health Disparities Through Adoption of Electronic Health Records. Psychiatr Serv 66:985-7
Smith, Selina A; Sheats, Joyce Q; Whitehead, Mary S et al. (2015) Developing a Cookbook with Lifestyle Tips: A Community-Engaged Approach to Promoting Diet-Related Cancer Prevention Guidelines. Jacobs J Food Nutr 2:
Lokko, Carl; Turner, Jacquelyn; Yoo, Wonsuk et al. (2015) Anal Squamous Cell Carcinoma in African Americans with and without HIV: A Comparative Study. J Cancer Epidemiol Treat 1:6-10

Showing the most recent 10 out of 77 publications