This application is for continuation of the existing partnership between Morehouse School of Medicine (MSM), Tuskegee University (TU), and the University of Alabama at Birmingham (UAB) Comprehensive Cancer Center (UABCCC). The three institutions, each serving a community with major black-white racial disparities, possess unique sets of strengths that complement each other. The primary objectives are to maintain progress in establishment of effective cancer research programs at MSM and TU and to persist In developing a pipeline of prospective minority Investigators at TU. The Partnership, with four effective Research Programs In education, research, career progression, and cancer outreach, will continue: 1) to tap the pool of talented students and faculty currently at MSM and TU through an effective Research Training and Career Development (RTCD) Program, linking them to established investigators and to the research Infrastructure at the UABCCC;2) to promote a Developmental Research Program, which provides funding opportunities to conduct research projects in parallel to the RTCD Program;3) to encourage postdoctoral fellows, graduate students, and undergraduates across scientific disciplines to pursue careers in the biosciences through our Cancer Education Program and to provide a pipeline into our RTCD and Developmental Research Programs;and, 4) through our established Community Outreach (now Cancer Outreach) Program, to promote cancer screening and healthy lifestyles among our most underserved populations and increase minority participation in therapeutic clinical trials. The partnership has two Interactive Shared Resources: 1) The Bioethics Shared Resource promotes and ensures adherence to bioethical principles and addresses ethical considerations in relationships between majority and minority institutions and between institutions and underserved communities;and 2) The Biostatistics Shared Resource maintains statistical support to all programs ofthe Partnership. With continued accomplishments, this partnership will provide the UABCCC, MSM, and TU with an enhanced capability to conduct research on cancer health disparities.

Public Health Relevance

This project will address the disparity in cancer incidence and mortality between African Americans and other racial/ethnic groups. It will help to build cancer research programs at two historically black Institutions of higher education -- Morehouse School of Medicine and Tuskegee University - and will encourage research on cancer disparities at one of the country's leading Comprehensive Cancer Centers, the University of Alabama at Birmingham CCC

National Institute of Health (NIH)
Specialized Center--Cooperative Agreements (U54)
Project #
Application #
Study Section
Special Emphasis Panel (ZCA1)
Program Officer
Ogunbiyi, Peter
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Morehouse School of Medicine
Public Health & Prev Medicine
Schools of Medicine
United States
Zip Code
Samuel, Temesgen; Fadlalla, Khalda; Gales, Dominique N et al. (2014) Variable NF-?B pathway responses in colon cancer cells treated with chemotherapeutic drugs. BMC Cancer 14:599
Battle, Monica; Gillespie, Corey; Quarshie, Alexander et al. (2014) Obesity induced a leptin-Notch signaling axis in breast cancer. Int J Cancer 134:1605-16
Singh, Rajesh; Gupta, Pranav; Kloecker, Goetz H et al. (2014) Expression and clinical significance of CXCR5/CXCL13 in human non?small cell lung carcinoma. Int J Oncol 45:2232-40
Desai, Arpita; Xu, Jingyao; Aysola, Kartik et al. (2014) Epithelial ovarian cancer: An overview. World J Transl Med 3:1-8
Colbert, Laronna S; Wilson, Kaamilah; Kim, Sungjin et al. (2014) NILCO biomarkers in breast cancer from Chinese patients. BMC Cancer 14:249
Smith, Selina A; Blumenthal, Daniel S (2013) Efficacy to effectiveness transition of an Educational Program to Increase Colorectal Cancer Screening (EPICS): study protocol of a cluster randomized controlled trial. Implement Sci 8:86
Coleman Wallace, Debbie A; Baltrus, Peter T; Wallace, Tracey C et al. (2013) Black white disparities in receiving a physician recommendation for colorectal cancer screening and reasons for not undergoing screening. J Health Care Poor Underserved 24:1115-24
Qin, Yunlong; Xu, Jingyao; Aysola, Kartik et al. (2011) Ubc9 mediates nuclear localization and growth suppression of BRCA1 and BRCA1a proteins. J Cell Physiol 226:3355-67
Caplan, Lee; Stout, Charlotte; Blumenthal, Daniel S (2011) Training physicians to do office-based smoking cessation increases adherence to PHS guidelines. J Community Health 36:238-43
Fortson, Wendell S; Kayarthodi, Shubhalaxmi; Fujimura, Yasuo et al. (2011) Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells. Int J Oncol 39:111-9

Showing the most recent 10 out of 13 publications