Core #3 Small Animal Imaging Sunkuk Kwon, Ph.D. The Small Animal Imaging facility depicted schematically in the Resource pages has been set up as a costcenter for BCM faculty. Rates are approved by BCM for charge on federal grants and investigators who use the facility are responsible for charges. The Small Animal Imaging Facility opened to the BCM and outside faculty in July 2006 and is not yet supported by any mechanism. Since July 2006, """"""""customers"""""""" included Rice University, LI-COR, Cardiology, Surgery (2), Neurosurgery, Pediatrics (2), CCAGT, The Breast Center, Becton- Dickinson, and others. Internal and external Investigators wishing to use the facility must first meet with Drs. Sevick and Kwon to discuss their scientific problem for which they seek to use small animal imaging. If a suitable imaging solution exists, the investigators must comply with BCM assurances associated with radioactivity, biohazards, hazardous materials, and IACUC protocols. If protocol and regulatory assurances need to be addressed, then a rate of $270/hr is charged. Usually, imaging procedures fall under Dr. Sevick's general animal protocols and assurances, and there is little administrative delay or cost in starting the project. Typically within BCM, investigators transfer their animals onto Dr. Sevick's IACUC protocols for the process of imaging, and then they are transferred back onto the investigator's protocols. The project is scheduled in the Center and animals are generally housed within the Frensley barrier with housing charged to the investigator. Participants can participate in the imaging process or simply request the experimental imaging procedures are conducted.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA136404-05
Application #
8381302
Study Section
Special Emphasis Panel (ZCA1-SRRB-9)
Project Start
Project End
2014-08-31
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
5
Fiscal Year
2012
Total Cost
$32,111
Indirect Cost
$10,394
Name
University of Texas Health Science Center Houston
Department
Type
DUNS #
800771594
City
Houston
State
TX
Country
United States
Zip Code
77225
Rasmussen, John C; Aldrich, Melissa B; Tan, I-Chih et al. (2016) Lymphatic transport in patients with chronic venous insufficiency and venous leg ulcers following sequential pneumatic compression. J Vasc Surg Venous Lymphat Disord 4:9-17
Gonzalez-Garay, M L; Aldrich, M B; Rasmussen, J C et al. (2016) A novel mutation in CELSR1 is associated with hereditary lymphedema. Vasc Cell 8:1
Zhu, Banghe; Rasmussen, John C; Litorja, Maritoni et al. (2016) Determining the Performance of Fluorescence Molecular Imaging Devices Using Traceable Working Standards With SI Units of Radiance. IEEE Trans Med Imaging 35:802-11
Wang, Xuejuan; Aldrich, Melissa B; Yang, Zhi et al. (2016) Influence of chelator and near-infrared dye labeling on biocharacteristics of dual-labeled trastuzumab-based imaging agents. Chin J Cancer Res 28:362-9
Zhu, B; Sevick-Muraca, E M (2015) A review of performance of near-infrared fluorescence imaging devices used in clinical studies. Br J Radiol 88:20140547
Gao, Peng; Pinkston, Kenneth L; Wilganowski, Nathaniel et al. (2015) Deglycosylation of mAb by EndoS for improved molecular imaging. Mol Imaging Biol 17:195-203
Rasmussen, John C; Fife, Caroline E; Sevick-Muraca, Eva M (2015) Near-Infrared Fluorescence Lymphatic Imaging in Lymphangiomatosis. Lymphat Res Biol 13:195-201
Ghosh, Sukhen C; Pinkston, Kenneth L; Robinson, Holly et al. (2015) Comparison of DOTA and NODAGA as chelators for (64)Cu-labeled immunoconjugates. Nucl Med Biol 42:177-83
Agollah, Germaine D; Gonzalez-Garay, Manuel L; Rasmussen, John C et al. (2014) Evidence for SH2 domain-containing 5'-inositol phosphatase-2 (SHIP2) contributing to a lymphatic dysfunction. PLoS One 9:e112548
Rasmussen, John C; Herbst, Karen L; Aldrich, Melissa B et al. (2014) An abnormal lymphatic phenotype is associated with subcutaneous adipose tissue deposits in Dercum's disease. Obesity (Silver Spring) 22:2186-92

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