The primary project comprises the essence of this program and spans the areas of investigation from targets and molecular probes to clinical evaluation. Dr Contag is the PI of the primary project and it is comprised of four specific aims that are well integrated with regard to scientific execution and participation by Stanford scientists and those at other institutions..

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA136465-05
Application #
8379279
Study Section
Special Emphasis Panel (ZCA1-SRRB-9)
Project Start
Project End
2014-08-31
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
5
Fiscal Year
2012
Total Cost
$652,816
Indirect Cost
$155,330
Name
Stanford University
Department
Type
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305
Uddin, Md Jashim; Moore, Chauca E; Crews, Brenda C et al. (2016) Fluorocoxib A enables targeted detection of cyclooxygenase-2 in laser-induced choroidal neovascularization. J Biomed Opt 21:90503
Uddin, Md Jashim; Werfel, Thomas A; Crews, Brenda C et al. (2016) Fluorocoxib A loaded nanoparticles enable targeted visualization of cyclooxygenase-2 in inflammation and cancer. Biomaterials 92:71-80
Sensarn, Steven; Zavaleta, Cristina L; Segal, Ehud et al. (2016) A Clinical Wide-Field Fluorescence Endoscopic Device for Molecular Imaging Demonstrating Cathepsin Protease Activity in Colon Cancer. Mol Imaging Biol 18:820-829
Templeton, Zachary S; Bachmann, Michael H; Alluri, Rajiv V et al. (2015) Methods for culturing human femur tissue explants to study breast cancer cell colonization of the metastatic niche. J Vis Exp :
Uddin, Md Jashim; Crews, Brenda C; Ghebreselasie, Kebreab et al. (2015) Targeted imaging of cancer by fluorocoxib C, a near-infrared cyclooxygenase-2 probe. J Biomed Opt 20:50502
Rogalla, Stephan; Contag, Christopher H (2015) Early Cancer Detection at the Epithelial Surface. Cancer J 21:179-87
Garai, Ellis; Sensarn, Steven; Zavaleta, Cristina L et al. (2015) A real-time clinical endoscopic system for intraluminal, multiplexed imaging of surface-enhanced Raman scattering nanoparticles. PLoS One 10:e0123185
Ra, Hyejun; González-González, Emilio; Uddin, Md Jashim et al. (2015) Detection of non-melanoma skin cancer by in vivo fluorescence imaging with fluorocoxib A. Neoplasia 17:201-7
Contag, Christopher H; Lie, Wen-Rong; Bammer, Marie C et al. (2014) Monitoring dynamic interactions between breast cancer cells and human bone tissue in a co-culture model. Mol Imaging Biol 16:158-66
Ajithkumar, G; Yoo, Benjamin; Goral, Dara E et al. (2013) Multimodal bioimaging using rare earth doped Gd2O2S: Yb/Er phosphor with upconversion luminescence and magnetic resonance properties. J Mater Chem A Mater 1:1561-1572

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