Dissemination and outreach to both tell the world what our PSOC is doing and attract those from outside the center to work with us is a key part of our mission. The main goals of this section of our proposed PSOC are (i) Dissemination to the physical science/cancer biology communities of our PSOC capabilities and results (11) Strategies and mechanisms to bring expertise outside ofthe PSOC into collaboration with us, leading to pilot projects The outreach and dissemination will be initially focused on educating those outside our PSOC interested in working with us on the capabilities and power of microfludic microhabitat patches in particular, which are at the heart of our proposed work, and the interface of microfluidics and biology research in general. (The microhabitat patches and microfluidics are described technically in detail in N2/Project 4 and the N4 Microfluidic Shared Resource Facility). These in practice will serve as the focal point for where the physical science meets the cancer biology in our Center. We will educate researchers not just in the background and capabilities in this field, but use the Microfluidic facility at Princeton to give them hands on training so that they can use such chips by themselves. The facility will be set up so that remote collaborators can first design and have chips made remotely, and then so that they will be able to remotely run and control microfluidic experiments in the facility at Princeton. Extended outside visitor programs will also be available, with a goal of developing collaborations and a pilot project. Thus those outside our PSOC can learn in detail what our unique talents are, and then can then propose meaningful collaborations between their labs and the PSOC in the form of a pilot project, or even transnetwork projects.
The main goals ofthis section of our proposed PSOC are (1) dissemination to the physical science/cancer biology communities of our PSOC capabilities and results, and (2) strategies and mechanisms to bring expertise outside ofthe PSOC into collaboration with us, leading to pilot projects.
|Jung, Younghun; Decker, Ann M; Wang, Jingcheng et al. (2016) Endogenous GAS6 and Mer receptor signaling regulate prostate cancer stem cells in bone marrow. Oncotarget 7:25698-711|
|Han, Weijing; Chen, Shaohua; Yuan, Wei et al. (2016) Oriented collagen fibers direct tumor cell intravasation. Proc Natl Acad Sci U S A 113:11208-11213|
|Yumoto, Kenji; Eber, Matthew R; Wang, Jingcheng et al. (2016) Axl is required for TGF-Î²2-induced dormancy of prostate cancer cells in the bone marrow. Sci Rep 6:36520|
|Piotrowski-Daspit, Alexandra S; Tien, Joe; Nelson, Celeste M (2016) Interstitial fluid pressure regulates collective invasion in engineered human breast tumors via Snail, vimentin, and E-cadherin. Integr Biol (Camb) 8:319-31|
|Gascard, Philippe; Tlsty, Thea D (2016) Carcinoma-associated fibroblasts: orchestrating the composition of malignancy. Genes Dev 30:1002-19|
|Amend, Sarah R; Roy, Sounak; Brown, Joel S et al. (2016) Ecological paradigms to understand the dynamics of metastasis. Cancer Lett 380:237-42|
|van der Toom, Emma E; Verdone, James E; Pienta, Kenneth J (2016) Disseminated tumor cells and dormancy in prostate cancer metastasis. Curr Opin Biotechnol 40:9-15|
|Amend, Sarah R; Valkenburg, Kenneth C; Pienta, Kenneth J (2016) Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation. J Vis Exp :|
|Lee, Eunsohl; Wang, Jingcheng; Yumoto, Kenji et al. (2016) DNMT1 Regulates Epithelial-Mesenchymal Transition and Cancer Stem Cells, Which Promotes Prostate Cancer Metastasis. Neoplasia 18:553-66|
|Pan, Deng; Roy, Somdutta; Gascard, Philippe et al. (2016) SOX2, OCT3/4 and NANOG expression and cellular plasticity in rare human somatic cells requires CD73. Cell Signal 28:1923-1932|
Showing the most recent 10 out of 84 publications