Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA143837-06
Application #
8564194
Study Section
Special Emphasis Panel (ZCA1-SRLB-9 (O1))
Project Start
2009-09-28
Project End
2015-07-31
Budget Start
2013-09-19
Budget End
2014-07-31
Support Year
Fiscal Year
2013
Total Cost
$189,226
Indirect Cost
$66,352
Name
Methodist Hospital Research Institute
Department
Type
DUNS #
185641052
City
Houston
State
TX
Country
United States
Zip Code
77030
Martinez, Jonathan O; Evangelopoulos, Michael; Bhavane, Rohan et al. (2015) Multistage Nanovectors Enhance the Delivery of Free and Encapsulated Drugs. Curr Drug Targets 16:1582-90
Corbo, Claudia; Parodi, Alessandro; Evangelopoulos, Michael et al. (2015) Proteomic Profiling of a Biomimetic Drug Delivery Platform. Curr Drug Targets 16:1540-7
Singh, Jaykrishna; Hussain, Fazle; Decuzzi, Paolo (2015) Role of differential adhesion in cell cluster evolution: from vasculogenesis to cancer metastasis. Comput Methods Biomech Biomed Engin 18:282-92
Wang, Zhihui; Butner, Joseph D; Kerketta, Romica et al. (2015) Simulating cancer growth with multiscale agent-based modeling. Semin Cancer Biol 30:70-8
Jaganathan, Hamsa; Mitra, Sucharita; Srinivasan, Srimeenakshi et al. (2014) Design and in vitro evaluation of layer by layer siRNA nanovectors targeting breast tumor initiating cells. PLoS One 9:e91986
Yang, Yong; Wolfram, Joy; Fang, Xiaohong et al. (2014) Polyarginine induces an antitumor immune response through binding to toll-like receptor 4. Small 10:1250-4
Koshkina, Nadezhda V; Briggs, Katrina; Palalon, Flavio et al. (2014) Autophagy and enhanced chemosensitivity in experimental pancreatic cancers induced by noninvasive radiofrequency field treatment. Cancer 120:480-91
Martinez, Jonathan O; Evangelopoulos, Michael; Karun, Vivek et al. (2014) The effect of multistage nanovector targeting of VEGFR2 positive tumor endothelia on cell adhesion and local payload accumulation. Biomaterials 35:9824-32
Gonzalez-Villasana, Vianey; Rodriguez-Aguayo, Cristian; Arumugam, Thiruvengadam et al. (2014) Bisphosphonates inhibit stellate cell activity and enhance antitumor effects of nanoparticle albumin-bound paclitaxel in pancreatic ductal adenocarcinoma. Mol Cancer Ther 13:2583-94
Koay, Eugene J; Truty, Mark J; Cristini, Vittorio et al. (2014) Transport properties of pancreatic cancer describe gemcitabine delivery and response. J Clin Invest 124:1525-36

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