The Education and Training Unit to develop and implement modules for integrative training for graduate and postdoctoral students and junior investigators. ETU will accomplish its mission by leverage the rich training infrastructure available across its collaborating institutions to provide a diverse and engaging experience for trainees. This existing multidisciplinary training infrastructure - which encompasses disciplines as diverse as biology, chemistry, physics and engineering -will provide ETU with: (1) a pool of graduate and postdoctoral trainees, as well as junior and senior investigators who participate as trainees and as mentors;(2) training environments and laboratories for hands-on training;and (3) didactic coursework and internal seminars. ETU will establish a 'Biology, Oncology, Physical Science &Engineering (BiOPSE) track by which trainees can engage in a set of didactic activities, seminars, research rotations in MC-START laboratories and clinical rotations over 2-3 years. We will develop three different sub-tracks within BiOPSE: (1) predoctoral;(2) postdoctoral;(3) junior investigator;and (4) senior investigator. A BiOPSE trainee's course of study will include three (2-year trainees) or six (for 3-year trainees) 2-month research rotations and an optional 1-month clinical rotation. Primary mentors will help structure coursework for trainees to assure that didactic experiences in cancer biology, physics, chemistry, mathematics, computing and engineering. The Banbury Conference Center will host a yearly course for all BiOPSE mentors, trainees, the MC-START Director, senior Co-I and other ETU training faculty. ETU also will utilize a distance learning approach that replies on a state-of-the-art cyberinfrastructure to stimulate development of lasting ties between institutions, schools, departments and centers with different cultures, and in order to enhance the triangulated communications between a trainee and two mentors, to communicate expectations of graduate students and expectations of the student/faculty relationship, and to centralize and make more broadly available critical resources;and mechanisms to exchange trainees among participating institutions.

Public Health Relevance

The Education and Training Unit will plan modules for integrative training and will develop mechanisms to exchange trainees. The orienting principle is to develop a truly multidisciplinary course of training that provides intensive learning experiences in cancer biology, physical sciences and engineering, in order to facilitate the development of a new cadre of researcher with expertise that spans these disciplines.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA143907-04
Application #
8381763
Study Section
Special Emphasis Panel (ZCA1-SRLB-9)
Project Start
Project End
Budget Start
2012-08-01
Budget End
2013-07-31
Support Year
4
Fiscal Year
2012
Total Cost
$98,936
Indirect Cost
Name
University of Southern California
Department
Type
DUNS #
072933393
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Flinders, Colin; Lam, Larry; Rubbi, Liudmilla et al. (2016) Epigenetic changes mediated by polycomb repressive complex 2 and E2a are associated with drug resistance in a mouse model of lymphoma. Genome Med 8:54
Sims, Lee B; Curtis, Louis T; Frieboes, Hermann B et al. (2016) Enhanced uptake and transport of PLGA-modified nanoparticles in cervical cancer. J Nanobiotechnology 14:33
Lee, Jung-Rok; Sato, Noriyuki; Bechstein, Daniel J B et al. (2016) Experimental and theoretical investigation of the precise transduction mechanism in giant magnetoresistive biosensors. Sci Rep 6:18692
Juarez, Edwin F; Lau, Roy; Friedman, Samuel H et al. (2016) Quantifying differences in cell line population dynamics using CellPD. BMC Syst Biol 10:92
Baugh, Evan H; Simmons-Edler, Riley; Müller, Christian L et al. (2016) Robust classification of protein variation using structural modelling and large-scale data integration. Nucleic Acids Res 44:2501-13
Li, Yulin; Deutzmann, Anja; Choi, Peter S et al. (2016) BIM mediates oncogene inactivation-induced apoptosis in multiple transgenic mouse models of acute lymphoblastic leukemia. Oncotarget 7:26926-34
Garvey, Colleen M; Spiller, Erin; Lindsay, Danika et al. (2016) A high-content image-based method for quantitatively studying context-dependent cell population dynamics. Sci Rep 6:29752
Lee, Jung-Rok; Bechstein, Daniel J B; Ooi, Chin Chun et al. (2016) Magneto-nanosensor platform for probing low-affinity protein-protein interactions and identification of a low-affinity PD-L1/PD-L2 interaction. Nat Commun 7:12220
Chiu, Chi-Li; Patsch, Katherin; Cutrale, Francesco et al. (2016) Intracellular kinetics of the androgen receptor shown by multimodal Image Correlation Spectroscopy (mICS). Sci Rep 6:22435
Hosoya, Hitomi; Dobroff, Andrey S; Driessen, Wouter H P et al. (2016) Integrated nanotechnology platform for tumor-targeted multimodal imaging and therapeutic cargo release. Proc Natl Acad Sci U S A 113:1877-82

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