There is a strong association between physical inactivity, metabolic dysfunction and several cancers. Observational studies have demonstrated that physical activity in cancer survivorship can lead to significantly improved quality of life, physical function, and disease free survival, including up to 40% reduction in recurrence and up to 50% reduction in mortality of colorectal and breast cancer. Relatively moderate amounts of physical activity may be needed to achieve these protective benefits, such as walking 30 minutes per day at about 2.5 miles per hour. None of these studies, however, were focused on Native American cancer survivors. Navajo are the largest group of Native Americans in Arizona and the U.S. and have the poorest 5-year cancer survival rate of any group in the country. Improving cancer survivorship among the Navajo is important given the high representation of Navajo in Arizona, the disproportionate burden of metabolic dysfunction,

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
2U54CA143924-06
Application #
8823200
Study Section
Special Emphasis Panel (ZCA1-SRLB-B (O1))
Project Start
2009-09-28
Project End
2019-08-31
Budget Start
2014-09-19
Budget End
2015-08-31
Support Year
6
Fiscal Year
2014
Total Cost
$118,802
Indirect Cost
$59,233
Name
University of Arizona
Department
Type
DUNS #
806345617
City
Tucson
State
AZ
Country
United States
Zip Code
85721
Batai, Ken; Harb-De la Rosa, Alfredo; Lwin, Aye et al. (2018) Racial and Ethnic Disparities in Renal Cell Carcinoma: An Analysis of Clinical Characteristics. Clin Genitourin Cancer :
Bea, J W; Hsu, C-H; Blew, R M et al. (2018) Use of iDXA spine scans to evaluate total and visceral abdominal fat. Am J Hum Biol 30:
Bokulich, Nicholas A; Dillon, Matthew R; Zhang, Yilong et al. (2018) q2-longitudinal: Longitudinal and Paired-Sample Analyses of Microbiome Data. mSystems 3:
Varadaraj, Archana; Magdaleno, Carina; Mythreye, Karthikeyan (2018) Deoxycholate Fractionation of Fibronectin (FN) and Biotinylation Assay to Measure Recycled FN Fibrils in Epithelial Cells. Bio Protoc 8:
Martinez, Jessica A; Yang, Jun; Wertheim, Betsy C et al. (2018) Celecoxib use and circulating oxylipins in a colon polyp prevention trial. PLoS One 13:e0196398
Yellowhair, Monica; Romanotto, Michelle R; Stearns, Diane M et al. (2018) Uranyl acetate induced DNA single strand breaks and AP sites in Chinese hamster ovary cells. Toxicol Appl Pharmacol 349:29-38
Bea, Jennifer W; de Heer, Hendrik Dirk; Valdez, Luis et al. (2018) Physical Activity among Navajo Cancer Survivors: A Qualitative Study. Am Indian Alsk Native Ment Health Res 25:54-73
Bokulich, Nicholas A; Kaehler, Benjamin D; Rideout, Jai Ram et al. (2018) Optimizing taxonomic classification of marker-gene amplicon sequences with QIIME 2's q2-feature-classifier plugin. Microbiome 6:90
Huenneke, Laura F; Stearns, Diane M; Martinez, Jesse D et al. (2017) Key Strategies for Building Research Capacity of University Faculty Members. Innov High Educ 42:421-435
Jim, Venessa; LaViolette, Corinne; Briehl, Margaret M et al. (2017) Spatial distribution of uranium in mice kidneys detected by laser ablation inductively coupled plasma mass spectrometry. J Appl Bioanal 3:43-48

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