The proposed partnership between Charles Drew University (CDU) and UCLA Jonsson Cancer Center seeks to "Eliminate Cancer Health Disparities in Minority and Underserved Populations". This objective will continue to strengthen the CDU cancer research and training infrastructure by enhancing the participation of minority students, fellows and faculty engaged in Cancer Research, Training, and Cancer Outreach. The partnership will continue to recruit new faculty with career focus in cancer research, education or outreach. Likewise, UCLA and the investigators in the JCCC will have the important opportunity to address, issues related to the unequal burden of cancer in minority populations. The partnership developed during our U56 funding has made a significant impact on our ability to develop strong pilots and partnership programs. A key new and important addition to our U54 program is the development of strong Cancer Outreach Program and Projects. Thereby, we will train more minority investigators addressing issues in cancer research, education, training and outcome in our communities. In view of the rapidly changing demographics of Los Angeles and the state of California, the CDU-UCLA Partnership is ideally situated and will have an opportunity to have a positive impact on reducing cancer incidence and improving survival in minority and underserved populations. The overarching goals of the CDU-UCLA Cancer Partnership Program are to significantly increase the number of minority scientists in cancer research and to enhance the cancer outreach programs at CDU to address significant disparities in cancer among minority populations. Supported and implemented by an Administrative Core, Planning and Evaluation Core, and Developmental Core, the basic program components are 1) research projects;2) the mentoring of students and junior investigators;3) the training seminar series;4) enhance CDU's integrated clinical and tissue biorepository data base on minority suubjects;5) enhance community participation;6) improve our clinical trials resource;and 7) increase faculty recruitment. We plan to submit 2 full projects and 2 pilot projects.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
3U54CA143931-05S2
Application #
8907370
Study Section
Special Emphasis Panel (ZCA1-SRLB-D (O2))
Program Officer
Moten, Carmen P
Project Start
2009-09-29
Project End
2015-08-31
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
5
Fiscal Year
2014
Total Cost
$188,559
Indirect Cost
$57,159
Name
Charles R. Drew University of Medicine & Science
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
785877408
City
Los Angeles
State
CA
Country
United States
Zip Code
90059
Wang, Piwen; Phan, Tien; Gordon, David et al. (2015) Arctigenin in combination with quercetin synergistically enhances the antiproliferative effect in prostate cancer cells. Mol Nutr Food Res 59:250-61
Lucas-Wright, Anna; Bazargan, Mohsen; Jones, Loretta et al. (2014) Correlates of perceived risk of developing cancer among African-Americans in South Los Angeles. J Community Health 39:173-80
Sarkissyan, Marianna; Wu, Yanyuan; Chen, Zujian et al. (2014) Vitamin D receptor FokI gene polymorphisms may be associated with colorectal cancer among African American and Hispanic participants. Cancer 120:1387-93
Kang, Henry H; Kang, Julia J; Kang, Hyung-Gyoo et al. (2014) Urothelial differentiation of human amniotic fluid stem cells by urothelium specific conditioned medium. Cell Biol Int 38:531-7
Fu, Maoyong; Maresh, Erin L; Helguera, Gustavo F et al. (2014) Rationale and preclinical efficacy of a novel anti-EMP2 antibody for the treatment of invasive breast cancer. Mol Cancer Ther 13:902-15
Ryu, So Yeon; Crespi, Catherine M; Maxwell, Annette E (2014) Colorectal cancer among Koreans living in South Korea versus California: incidence, mortality, and screening rates. Ethn Health 19:406-23
Wang, Piwen; Vadgama, Jaydutt V; Said, Jonathan W et al. (2014) Enhanced inhibition of prostate cancer xenograft tumor growth by combining quercetin and green tea. J Nutr Biochem 25:73-80
Wang, Piwen; Wang, Bin; Chung, Seyung et al. (2014) Increased chemopreventive effect by combining arctigenin, green tea polyphenol and curcumin in prostate and breast cancer cells. RSC Adv 4:35242-35250
Maxwell, Annette E; Young, Sandra; Rabelo Vega, Roena et al. (2014) Training Mixtec promotores to assess health concerns in their community: a CBPR pilot study. J Immigr Minor Health 16:310-3
Mishra, Dhruva K; Wu, Yanyuan; Sarkissyan, Marianna et al. (2013) Vitamin D receptor gene polymorphisms and prognosis of breast cancer among African-American and Hispanic women. PLoS One 8:e57967

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