Our component Outreach activities will be coordinated by a group of three individuals, two Boston-based and one Berkeley-based. Dr. Heiko Enderiing, Instructor of Medicine at CCSB, Tufts Univ. School of Medicine, will be the Lead on the Outreach. Dr. Enderiing is a highly accomplished modeler, with expertise in computational modeling of early tumor development He is a recent recipient of the prestigious AACR Centennial Postdoctoral Fellow in Cancer Research. Dr. Enderiing has experience and particular interest in education and the melding of mathematical and biological sciences. Clare Lament, also of CCSB at Tufts will Co-Lead the ICBP Outreach effort. She is the PI for the Outreach program on Dr. HIatky's NSCOR and has successfully orchestrated the many Outreach activities of that NASA-funded team over the last 3yrs, including working with an established film director to produce a feature video on the multi-disciplinary approach to quantify carcinogenesis risk for space travel. Rainer Sachs, Professor of Mathematics and Professor Emeritus of Physics at UCB, the Research PI on the Berkeley arm of this ICBP proposal, will also take a very active role in the Education and Training activities and oversee the Berkeley-based activities. All three individuals participated successfully in the already established, ongoing Outreach activities of the Center of Cancer Systems Biology Program (section N3 component 3 above). These three have worked closely together for a number of years through NSCOR and other activities.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Specialized Center--Cooperative Agreements (U54)
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Special Emphasis Panel (ZCA1-SRLB-C)
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Genesys Research Institute, Inc.
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Radivoyevitch, Tomas; Jankovic, Gradimir M; Tiu, Ramon V et al. (2014) Sex differences in the incidence of chronic myeloid leukemia. Radiat Environ Biophys 53:55-63
Weekes, Suzanne L; Barker, Brian; Bober, Sarah et al. (2014) A multicompartment mathematical model of cancer stem cell-driven tumor growth dynamics. Bull Math Biol 76:1762-82
Nguyen, David H; Ouyang, Haoxu; Mao, Jian-Hua et al. (2014) Distinct luminal-type mammary carcinomas arise from orthotopic Trp53-null mammary transplantation of juvenile versus adult mice. Cancer Res 74:7149-58
Benzekry, S├ębastien; Lamont, Clare; Beheshti, Afshin et al. (2014) Classical mathematical models for description and prediction of experimental tumor growth. PLoS Comput Biol 10:e1003800
Benzekry, S├ębastien; Gandolfi, Alberto; Hahnfeldt, Philip (2014) Global dormancy of metastases due to systemic inhibition of angiogenesis. PLoS One 9:e84249
Beheshti, Afshin; Peluso, Michael; Lamont, Clare et al. (2014) Proton irradiation augments the suppression of tumor progression observed with advanced age. Radiat Res 181:272-83
Gale, Robert Peter; Hlatky, Lynn; Sachs, Rainer K et al. (2014) Why is there so much therapy-related AML and MDS and so little therapy-related CML? Leuk Res 38:1162-4
Poleszczuk, J; Hahnfeldt, P; Enderling, H (2014) Biphasic modulation of cancer stem cell-driven solid tumour dynamics in response to reactivated replicative senescence. Cell Prolif 47:267-76
Prochazka, Vaclav; Klosova, Hana; Stetinsky, Jiri et al. (2014) Addition of platelet concentrate to dermo-epidermal skin graft in deep burn trauma reduces scarring and need for revision surgeries. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 158:242-58
Hlatky, Lynn; Hahnfeldt, Philip (2014) Beyond the cancer cell: progression-level determinants highlight the multiscale nature of carcinogenesis risk. Cancer Res 74:659-64

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