Our component Outreach activities will be coordinated by a group of three individuals, two Boston-based and one Berkeley-based. Dr. Heiko Enderiing, Instructor of Medicine at CCSB, Tufts Univ. School of Medicine, will be the Lead on the Outreach. Dr. Enderiing is a highly accomplished modeler, with expertise in computational modeling of early tumor development He is a recent recipient of the prestigious AACR Centennial Postdoctoral Fellow in Cancer Research. Dr. Enderiing has experience and particular interest in education and the melding of mathematical and biological sciences. Clare Lament, also of CCSB at Tufts will Co-Lead the ICBP Outreach effort. She is the PI for the Outreach program on Dr. HIatky's NSCOR and has successfully orchestrated the many Outreach activities of that NASA-funded team over the last 3yrs, including working with an established film director to produce a feature video on the multi-disciplinary approach to quantify carcinogenesis risk for space travel. Rainer Sachs, Professor of Mathematics and Professor Emeritus of Physics at UCB, the Research PI on the Berkeley arm of this ICBP proposal, will also take a very active role in the Education and Training activities and oversee the Berkeley-based activities. All three individuals participated successfully in the already established, ongoing Outreach activities of the Center of Cancer Systems Biology Program (section N3 component 3 above). These three have worked closely together for a number of years through NSCOR and other activities.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA149233-04
Application #
8536739
Study Section
Special Emphasis Panel (ZCA1-SRLB-C)
Project Start
Project End
Budget Start
2013-03-01
Budget End
2014-02-28
Support Year
4
Fiscal Year
2013
Total Cost
$46,096
Indirect Cost
Name
Genesys Research Institute, Inc.
Department
Type
DUNS #
965467512
City
Boston
State
MA
Country
United States
Zip Code
02135
Gao, Xuefeng; Sishc, Brock J; Nelson, Christopher B et al. (2016) Radiation-Induced Reprogramming of Pre-Senescent Mammary Epithelial Cells Enriches Putative CD44(+)/CD24(-/low) Stem Cell Phenotype. Front Oncol 6:138
Benzekry, Sebastien; Beheshti, Afshin; Hahnfeldt, Philip et al. (2015) Capturing the Driving Role of Tumor-Host Crosstalk in a Dynamical Model of Tumor Growth. Bio Protoc 5:
Wage, Justin; Ma, Lili; Peluso, Michael et al. (2015) Proton irradiation impacts age-driven modulations of cancer progression influenced by immune system transcriptome modifications from splenic tissue. J Radiat Res 56:792-803
Kareva, Irina; Waxman, David J; Lakka Klement, Giannoula (2015) Metronomic chemotherapy: an attractive alternative to maximum tolerated dose therapy that can activate anti-tumor immunity and minimize therapeutic resistance. Cancer Lett 358:100-6
Radivoyevitch, Tomas; Siranart, Nopphon; Hlatky, Lynn et al. (2015) Stochastic process pharmacodynamics: dose timing in neonatal gentamicin therapy as an example. AAPS J 17:447-56
Beheshti, Afshin; Wage, Justin; McDonald, J Tyson et al. (2015) Tumor-host signaling interaction reveals a systemic, age-dependent splenic immune influence on tumor development. Oncotarget 6:35419-32
Benzekry, Sebastian; Tuszynski, Jack A; Rietman, Edward A et al. (2015) Design principles for cancer therapy guided by changes in complexity of protein-protein interaction networks. Biol Direct 10:32
Pellicciotta, Ilenia; Marciscano, Ariel E; Hardee, Matthew E et al. (2015) Development of a novel multiplexed assay for quantification of transforming growth factor-β (TGF-β). Growth Factors 33:79-91
Beheshti, Afshin; Benzekry, Sébastien; McDonald, J Tyson et al. (2015) Host age is a systemic regulator of gene expression impacting cancer progression. Cancer Res 75:1134-43
Beheshti, Afshin; Peluso, Michael; Lamont, Clare et al. (2014) Proton irradiation augments the suppression of tumor progression observed with advanced age. Radiat Res 181:272-83

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