4.1 Organization and Functioning The DCCNE Administrative Core will be led by the Director, Dr. lan Baker, who will partner with the NCCC Associate Director for Administration and Scientific Affairs, Mr. Robert Geriach. to define a robust administrative infrastructure to facilitate the work of the proposed center. Components of the effort will include supporting the deliberations of the DCCNE Steering Committee, maintaining active interaction with the NCI Alliance and is Coordinating and Governance Committee, and maintaining highly integrated, efficient, and proactive administrative systems to foster the effectiveness ofthe individual elements ofthe DCCNE and its collaborative efforts. The Administrative Core can provide the DCCNE with a tangible, physical presence on the Dartmouth campus. It will be housed in the NCCC Rubin Building on the Dartmouth-Hitchcock campus, in close proximity to the meeting rooms that support the gatherings of NCCC research programs and clinical services groups, to facilitate participation ofthe faculty with clinical responsibilities. The DCCNE Administrative Core can build on a history of active interaction among faculty with interest in the application of biomedical engineering to the clinical challenges of oncology care. NCCC Administration currently supports a monthly research meeting ofthe members of its Cancer Imaging and Radiobiology Program. These gatherings have combined discussion of current research, and the fostering of new collaborative, with hosting internal and external seminar speakers. With regard to nanotechnology, the Cancer Nanotechnology Working Group (CNWG) has organized (Drs. Gibson and Hoopes) a seminar series as a focal point for discussion of work relevant to these considerations. Dr. Hoopes convenes a weekly Nanoparticle Hyperthermia Group meeting (Mondays at noon), and Dr. Baker organizes a weekly (Tu/Th 10-12) series of discussions focusing on nanomaterials. Of particular relevance to DCCNE is a weekly focus-group meeting led by Dr. Paulsen, addressing breast imaging research;this meeting includes interaction between the bioengineering faculty and clinicians from NCCC's Breast Cancer Oncology Group.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA151662-04
Application #
8545107
Study Section
Special Emphasis Panel (ZCA1-GRB-S)
Project Start
Project End
Budget Start
2013-08-01
Budget End
2014-07-31
Support Year
4
Fiscal Year
2013
Total Cost
$251,397
Indirect Cost
$76,627
Name
Dartmouth College
Department
Type
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755
Rutkowski, Melanie R; Stephen, Tom L; Svoronos, Nikolaos et al. (2015) Microbially driven TLR5-dependent signaling governs distal malignant progression through tumor-promoting inflammation. Cancer Cell 27:27-40
Stephen, Tom L; Rutkowski, Melanie R; Allegrezza, Michael J et al. (2014) Transforming growth factor ?-mediated suppression of antitumor T cells requires FoxP1 transcription factor expression. Immunity 41:427-39
Reeves, Daniel B; Weaver, John B (2014) Approaches for modeling magnetic nanoparticle dynamics. Crit Rev Biomed Eng 42:85-93
Toraya-Brown, Seiko; Sheen, Mee Rie; Zhang, Peisheng et al. (2014) Local hyperthermia treatment of tumors induces CD8(+) T cell-mediated resistance against distal and secondary tumors. Nanomedicine 10:1273-85
Tichauer, Kenneth M; Deharvengt, Sophie J; Samkoe, Kimberley S et al. (2014) Tumor endothelial marker imaging in melanomas using dual-tracer fluorescence molecular imaging. Mol Imaging Biol 16:372-82
Tichauer, Kenneth M; Samkoe, Kimberley S; Gunn, Jason R et al. (2014) Microscopic lymph node tumor burden quantified by macroscopic dual-tracer molecular imaging. Nat Med 20:1348-53
Samkoe, Kimberley S; Tichauer, Kenneth M; Gunn, Jason R et al. (2014) Quantitative in vivo immunohistochemistry of epidermal growth factor receptor using a receptor concentration imaging approach. Cancer Res 74:7465-74
Perreard, I M; Reeves, D B; Zhang, X et al. (2014) Temperature of the magnetic nanoparticle microenvironment: estimation from relaxation times. Phys Med Biol 59:1109-19
Ficko, Bradley W; Nadar, Priyanka M; Hoopes, P Jack et al. (2014) Development of a magnetic nanoparticle susceptibility magnitude imaging array. Phys Med Biol 59:1047-71
Russell, Stewart; Samkoe, Kimberley S; Gunn, Jason R et al. (2014) Spatial frequency analysis of anisotropic drug transport in tumor samples. J Biomed Opt 19:15005

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