4.1 Organization and Functioning The DCCNE Administrative Core will be led by the Director, Dr. lan Baker, who will partner with the NCCC Associate Director for Administration and Scientific Affairs, Mr. Robert Geriach. to define a robust administrative infrastructure to facilitate the work of the proposed center. Components of the effort will include supporting the deliberations of the DCCNE Steering Committee, maintaining active interaction with the NCI Alliance and is Coordinating and Governance Committee, and maintaining highly integrated, efficient, and proactive administrative systems to foster the effectiveness ofthe individual elements ofthe DCCNE and its collaborative efforts. The Administrative Core can provide the DCCNE with a tangible, physical presence on the Dartmouth campus. It will be housed in the NCCC Rubin Building on the Dartmouth-Hitchcock campus, in close proximity to the meeting rooms that support the gatherings of NCCC research programs and clinical services groups, to facilitate participation ofthe faculty with clinical responsibilities. The DCCNE Administrative Core can build on a history of active interaction among faculty with interest in the application of biomedical engineering to the clinical challenges of oncology care. NCCC Administration currently supports a monthly research meeting ofthe members of its Cancer Imaging and Radiobiology Program. These gatherings have combined discussion of current research, and the fostering of new collaborative, with hosting internal and external seminar speakers. With regard to nanotechnology, the Cancer Nanotechnology Working Group (CNWG) has organized (Drs. Gibson and Hoopes) a seminar series as a focal point for discussion of work relevant to these considerations. Dr. Hoopes convenes a weekly Nanoparticle Hyperthermia Group meeting (Mondays at noon), and Dr. Baker organizes a weekly (Tu/Th 10-12) series of discussions focusing on nanomaterials. Of particular relevance to DCCNE is a weekly focus-group meeting led by Dr. Paulsen, addressing breast imaging research;this meeting includes interaction between the bioengineering faculty and clinicians from NCCC's Breast Cancer Oncology Group.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Specialized Center--Cooperative Agreements (U54)
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Special Emphasis Panel (ZCA1-GRB-S)
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Dartmouth College
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Hoopes, P Jack; Wagner, Robert J; Duval, Kayla et al. (2018) Treatment of Canine Oral Melanoma with Nanotechnology-Based Immunotherapy and Radiation. Mol Pharm 15:3717-3722
Pearce, John A; Petryk, Alicia A; Hoopes, P Jack (2017) Numerical Model Study of In Vivo Magnetic Nanoparticle Tumor Heating. IEEE Trans Biomed Eng 64:2813-2823
Fang, Yongliang; Chu, Thach H; Ackerman, Margaret E et al. (2017) Going native: Direct high throughput screening of secreted full-length IgG antibodies against cell membrane proteins. MAbs 9:1253-1261
Hoopes, P Jack; Wagner, Robert J; Song, Ailin et al. (2017) The effect of hypofractionated radiation and magnetic nanoparticle hyperthermia on tumor immunogenicity and overall treatment response. Proc SPIE Int Soc Opt Eng 10066:
Hoopes, P Jack; Moodie, Karen L; Petryk, Alicia A et al. (2017) Hypo-fractionated Radiation, Magnetic Nanoparticle Hyperthermia and a Viral Immunotherapy Treatment of Spontaneous Canine Cancer. Proc SPIE Int Soc Opt Eng 10066:
Ficko, Bradley W; NDong, Christian; Giacometti, Paolo et al. (2017) A Feasibility Study of Nonlinear Spectroscopic Measurement of Magnetic Nanoparticles Targeted to Cancer Cells. IEEE Trans Biomed Eng 64:972-979
Hoopes, P Jack; Mazur, Courtney M; Osterberg, Bjorn et al. (2017) Effect of intra-tumoral magnetic nanoparticle hyperthermia and viral nanoparticle immunogenicity on primary and metastatic cancer. Proc SPIE Int Soc Opt Eng 10066:
Tesone, Amelia J; Rutkowski, Melanie R; Brencicova, Eva et al. (2016) Satb1 Overexpression Drives Tumor-Promoting Activities in Cancer-Associated Dendritic Cells. Cell Rep 14:1774-1786
Davis, Scott C; Tichauer, Kenneth M (2016) Small-Animal Imaging Using Diffuse Fluorescence Tomography. Methods Mol Biol 1444:123-37
Reeves, Daniel B; Shi, Yipeng; Weaver, John B (2016) Generalized Scaling and the Master Variable for Brownian Magnetic Nanoparticle Dynamics. PLoS One 11:e0150856

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