The Nanoparticle Engineering Core will support the research projects by providing comprehensive capabilities for the synthesis, functionalization, and characterization of nanoparticles. Our central hypothesis in creating this core is that the development of reliable nanoparticle-based diagnostic and therapeutic techniques requires that the physicochemical properties of the nanoparticles are well characterized, and hence well defined.
Specific Aims Aim 1. To provide expertise and assistance in the characterization of the physicochemical properties of nanoparticles synthesized or purchased in the research projects.
Aim 2. To develop new protocols for nanoparticle engineering to advance the research projects in the Center.
|Stark, Alejandro; Shin, Dong Jin; Pisanic 2nd, Thomas et al. (2016) A parallelized microfluidic DNA bisulfite conversion module for streamlined methylation analysis. Biomed Microdevices 18:5|
|Attaluri, Anilchandra; Seshadri, Madhav; Mirpour, Sahar et al. (2016) Image-guided thermal therapy with a dual-contrast magnetic nanoparticle formulation: A feasibility study. Int J Hyperthermia 32:543-57|
|Williford, John-Michael; Archang, Maani M; Minn, Il et al. (2016) Critical Length of PEG Grafts on lPEI/DNA Nanoparticles for Efficient in Vivo Delivery. ACS Biomater Sci Eng 2:567-578|
|Mukherjee, Amarnath; Kumar, Binod; Hatano, Koji et al. (2016) Development and Application of a Novel Model System to Study "Active" and "Passive" Tumor Targeting. Mol Cancer Ther 15:2541-2550|
|Yan, Lesan; Li, Xingde (2016) Biodegradable Stimuli-Responsive Polymeric Micelles for Treatment of Malignancy. Curr Pharm Biotechnol 17:227-36|
|Lesniak, Wojciech G; Oskolkov, Nikita; Song, Xiaolei et al. (2016) Salicylic Acid Conjugated Dendrimers Are a Tunable, High Performance CEST MRI NanoPlatform. Nano Lett 16:2248-53|
|Huang, Yu-Ja; Hoffmann, Gwendolyn; Wheeler, Benjamin et al. (2016) Cellular microenvironment modulates the galvanotaxis of brain tumor initiating cells. Sci Rep 6:21583|
|Dawidczyk, Charlene M; Russell, Luisa M; Searson, Peter C (2015) Recommendations for Benchmarking Preclinical Studies of Nanomedicines. Cancer Res 75:4016-20|
|Behnam Azad, Babak; Banerjee, Sangeeta R; Pullambhatla, Mrudula et al. (2015) Evaluation of a PSMA-targeted BNF nanoparticle construct. Nanoscale 7:4432-42|
|Song, Xiaolei; Airan, Raag D; Arifin, Dian R et al. (2015) Label-free in vivo molecular imaging of underglycosylated mucin-1 expression in tumour cells. Nat Commun 6:6719|
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