The Nanoparticle Engineering Core will support the research projects by providing comprehensive capabilities for the synthesis, functionalization, and characterization of nanoparticles. Our central hypothesis in creating this core is that the development of reliable nanoparticle-based diagnostic and therapeutic techniques requires that the physicochemical properties of the nanoparticles are well characterized, and hence well defined.
Specific Aims Aim 1. To provide expertise and assistance in the characterization of the physicochemical properties of nanoparticles synthesized or purchased in the research projects.
Aim 2. To develop new protocols for nanoparticle engineering to advance the research projects in the Center.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA151838-05
Application #
8734340
Study Section
Special Emphasis Panel (ZCA1-GRB-S)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
5
Fiscal Year
2014
Total Cost
$118,979
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
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Yang, Xing; Yadav, Nirbhay N; Song, Xiaolei et al. (2014) Tuning phenols with Intra-Molecular bond Shifted HYdrogens (IM-SHY) as diaCEST MRI contrast agents. Chemistry 20:15824-32

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