Developmental activities at the proposed NU-CCNE will include three components: Pilot Projects, Alliance Challenge Projects, and trans-Alliance activities. The current NU-CCNE has provided funding for pilot projects each year since its inception in 2005, and this program has been shown to be of critical importance in encouraging new and innovative ideas that will push the envelope ofthe current research and have potential to significantly enhance and advance research goals. Previously funded pilot projects have laid the groundwork for important new efforts and/or have been incorporated into the existing CCNE research portfolio. The new NU-CCNE will fund in-Center Pilot Projects, and proposes to expand this mechanism to inter-Alliance projects. These proposals will involve other Centers and Platforms across the Alliance network through synergistic projects that have the capacity to rapidly develop and advance technologies to the clinic by sharing the unique resources and strengths of the NU-CCNE. Finally, we will continue to contribute to trans-Alliance activities in order to build the Alliance community and encourage synergism by establishing a Bioinformatics Core to ensure information and data sharing, by participating in and assisting with the bulletins, and CCNE operation manuals.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA151880-05
Application #
8710066
Study Section
Special Emphasis Panel (ZCA1-GRB-S)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
5
Fiscal Year
2014
Total Cost
$113,166
Indirect Cost
Name
Northwestern University at Chicago
Department
Type
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Seo, Soyoung E; Wang, Mary X; Shade, Chad M et al. (2016) Modulating the Bond Strength of DNA-Nanoparticle Superlattices. ACS Nano 10:1771-9
Thaner, Ryan V; Eryazici, Ibrahim; Macfarlane, Robert J et al. (2016) The Significance of Multivalent Bonding Motifs and ""Bond Order"" in DNA-Directed Nanoparticle Crystallization. J Am Chem Soc 138:6119-22
Thaxton, C Shad; Rink, Jonathan S; Naha, Pratap C et al. (2016) Lipoproteins and lipoprotein mimetics for imaging and drug delivery. Adv Drug Deliv Rev 106:116-131
Culver, Kayla S B; Shin, Yu Jin; Rotz, Matthew W et al. (2016) Shape-Dependent Relaxivity of Nanoparticle-Based T1 Magnetic Resonance Imaging Contrast Agents. J Phys Chem C Nanomater Interfaces 120:22103-22109
Moore, Laura; Yang, Junyu; Lan, Thanh T Ha et al. (2016) Biocompatibility Assessment of Detonation Nanodiamond in Non-Human Primates and Rats Using Histological, Hematologic, and Urine Analysis. ACS Nano 10:7385-400
Barnaby, Stacey N; Perelman, Grant A; Kohlstedt, Kevin L et al. (2016) Design Considerations for RNA Spherical Nucleic Acids (SNAs). Bioconjug Chem 27:2124-31
Hung, Andy H; Lilley, Laura M; Hu, Fengqin et al. (2016) Magnetic barcode imaging for contrast agents. Magn Reson Med :
Wang, Xiao; Hao, Liangliang; Bu, Heng-Fu et al. (2016) Spherical nucleic acid targeting microRNA-99b enhances intestinal MFG-E8 gene expression and restores enterocyte migration in lipopolysaccharide-induced septic mice. Sci Rep 6:31687
Holbrook, Robert J; Rammohan, Nikhil; Rotz, Matthew W et al. (2016) Gd(III)-Dithiolane Gold Nanoparticles for T1-Weighted Magnetic Resonance Imaging of the Pancreas. Nano Lett 16:3202-9
Angeloni, Nicholas L; McMahon, Kaylin M; Swaminathan, Suchitra et al. (2016) Pathways for Modulating Exosome Lipids Identified By High-Density Lipoprotein-Like Nanoparticle Binding to Scavenger Receptor Type B-1. Sci Rep 6:22915

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