The disproportionate burden of CRC persists among racial-ethnic minorities and other medically underserved populations despite increased availability of beneficial screening tests. To address this gap, we propose an innovative theory-based educational intervention delivered in federally qualified health centers and health department clinics to improve patient awareness about colorectal cancer screening (CRCS), facilitate patient-provider discussion of CRCS, and increase uptake of CRCS among average risk individuals. We build on our established community-academic partnerships and the community-based participatory research framework as the foundation for a two-phase project entitled """"""""Colorectal Cancer Awareness, Research, Education and Screening"""""""" (CARES).
The aim of Phase 1 (year 1) is to design and produce a CARES toolkit consisting of a DVD and photonovella booklet, screening readiness card, and reminder postcard intended for a diverse medically underserved population. A total of 107 individuals will take part in the formative research, which uses a health literacy framework as a basis for developing the educational tool kit. In Phase 11 (Years 2-5), the aims ofthe prospective, longitudinal, randomized communitybased intervention study are to: assess efficacy of CARES tool kit vs. a standard brochure intervention (SI) on CRCS uptake;assess whether Preventive Health Model variables mediate intervention effects;and examine cost-effectiveness. In this phase, a total of 420 men and women aged 50-75 years, will be recruited and randomized to either the CARES condition or SI (210 in each arm). Both groups will receive free immunochemical fecal occult blood test (1-FOBT) kits as part of the intervention. I-FOBT and overall (any test) screening uptake will be evaluated at 12 months and compared between conditions. It is expected that the CARES intervention will be associated with greater screening uptake (FOBT and other screening) and cost effectiveness that the SI condition. Multivariable regression analysis will be used to assess factors associated with intervention effects.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA153509-05
Application #
8721352
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
5
Fiscal Year
2014
Total Cost
Indirect Cost
Name
H. Lee Moffitt Cancer Center & Research Institute
Department
Type
DUNS #
City
Tampa
State
FL
Country
United States
Zip Code
33612
Arevalo, Mariana; Jacobsen, Paul B; Gwede, Clement K et al. (2016) Development and validation of the biobanking attitudes and knowledge survey-Spanish (BANKS-SP). J Community Genet 7:303-314
Rivera, Y M; Vélez, H; Canales, J et al. (2016) When a Common Language Is Not Enough: Transcreating Cancer 101 for Communities in Puerto Rico. J Cancer Educ 31:776-783
Sehovic, Ivana; Gwede, Clement K; Meade, Cathy D et al. (2016) A Web-Based Platform for Educating Researchers About Bioethics and Biobanking. J Cancer Educ 31:397-404
Baik, Sharon H; Arevalo, Mariana; Gwede, Clement et al. (2016) Development and Validation of the Biomedical Research Trust Scale (BRTS) in English and Spanish. J Empir Res Hum Res Ethics :
Davis, Stacy N; Christy, Shannon M; Chavarria, Enmanuel A et al. (2016) A randomized controlled trial of a multicomponent, targeted, low-literacy educational intervention compared with a nontargeted intervention to boost colorectal cancer screening with fecal immunochemical testing in community clinics. Cancer :
Gwede, Clement K; Koskan, Alexis M; Quinn, Gwendolyn P et al. (2015) Patients' perceptions of colorectal cancer screening tests and preparatory education in federally qualified health centers. J Cancer Educ 30:294-300
Stanley, Jennifer; Klepczyk, Lisa; Keene, Kimberly et al. (2015) PARP1 and phospho-p65 protein expression is increased in human HER2-positive breast cancers. Breast Cancer Res Treat 150:569-79
Simmons, Vani Nath; Klasko, Lynne B; Fleming, Khaliah et al. (2015) Participatory evaluation of a community-academic partnership to inform capacity-building and sustainability. Eval Program Plann 52:19-26
Meade, Cathy D; Rodriguez, Elisa M; Arevalo, Mariana et al. (2015) Introducing Biospecimen Science to Communities: Tools from Two Cities. Prog Community Health Partnersh 9 Suppl:51-9
Dang, Julie H T; Rodriguez, Elisa M; Luque, John S et al. (2014) Engaging diverse populations about biospecimen donation for cancer research. J Community Genet 5:313-27

Showing the most recent 10 out of 20 publications