Biobanking is the collection, storage, and processing of human tissue and/or other biological specimens (biospecimens), often combined with medical and personal information, for research. Research indicates that most people have little knowledge about biobanking and may hold misconceptions about its purpose. A better understanding of people's perceptions of biobanking is hampered by the lack of validated instruments to evaluate knowledge about and attitudes towards biospecimen donation and banking. The Tampa Bay Community Cancer Network (TBCCN) has recently initiated research in biobanking, through the ARRA funded TBCCN Community Perceptions on Biobanking Project, which aims to design and produce educational communication priming tools (e.g., booklets, videos) about biospecimen collection and banking for healthy community members. The proposed project is the next step in a line of research aimed at testing the efficacy of English and Spanish language educational priming tools in promoting biospecimen collection and banking being developed through the TBCCN Community Perceptions on Biobanking Project.
The specific aims of the proposed study are to: (1): develop and pilot test instruments measuring knowledge of and attitudes toward biospecimen collection and biobanking, as well as intention to enroll in and donate specimens to a biobank;(2) conduct a pilot test evaluating educational communication priming tools in improving patients'knowledge of and attitudes towards cancer-related biobanking, as well as intention to donate biospecimens to a biobank;and (3) explore whether educational communication priming tools increase the rate of consent to donate blood to a biobank. The proposed project addresses gaps by developing and validating instruments to measure knowledge of and attitudes towards biospecimen donation and banking, as well as intention to donate biospecimens to a biobank (Phase 1). Once developed, these instruments will be used to evaluate the educational priming tools developed during the TBCCN Community Perceptions on Biobanking Project through a small randomized controlled trial (Phase 2). This trial will evaluate changes in attitudes toward biobanking, knowledge regarding biobanking, intention to participate in a biobank, and consent for donating blood to a biobank from patients provided either 1) educational communication priming tools about biobanking developed in the TBCCN Community Perceptions on Biobanking Project, or 2) the National Cancer Institute's brochure entitled "Providing Your Tissue for Research: What You Need to Know." The proposed pilot study will provide preliminary data to support a larger study of the superiority of the educational communication priming tools in improving patients'perceptions of biospecimen collection and biobanking.

Agency
National Institute of Health (NIH)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA153509-05
Application #
8721353
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
Budget End
Support Year
5
Fiscal Year
2014
Total Cost
Indirect Cost
Name
H. Lee Moffitt Cancer Center & Research Institute
Department
Type
DUNS #
City
Tampa
State
FL
Country
United States
Zip Code
33612
Gwede, Clement K; Koskan, Alexis M; Quinn, Gwendolyn P et al. (2015) Patients' perceptions of colorectal cancer screening tests and preparatory education in federally qualified health centers. J Cancer Educ 30:294-300
Quinn, Gwendolyn P; Koskan, Alexis; Sehovic, Ivana et al. (2014) Contrasting the ethical perspectives of biospecimen research among individuals with familial risk for hereditary cancer and biomedical researchers: implications for researcher training. Genet Test Mol Biomarkers 18:467-73
Dang, Julie H T; Rodriguez, Elisa M; Luque, John S et al. (2014) Engaging diverse populations about biospecimen donation for cancer research. J Community Genet 5:313-27
Koskan, Alexis; Klasko, Lynne; Davis, Stacy N et al. (2014) Use and taxonomy of social media in cancer-related research: a systematic review. Am J Public Health 104:e20-37
Greiner, K Allen; Friedman, Daniela B; Adams, Swann Arp et al. (2014) Effective recruitment strategies and community-based participatory research: community networks program centers' recruitment in cancer prevention studies. Cancer Epidemiol Biomarkers Prev 23:416-23
Vadaparampil, Susan T; Simmons, Vani N; Lee, Ji-Hyun et al. (2014) Journal clubs: an educational approach to advance understanding among community partners and academic researchers about CBPR and cancer health disparities. J Cancer Educ 29:122-8
Lee, Ji-Hyun; Fulp, William; Wells, Kristen J et al. (2014) Effect of patient navigation on time to diagnostic resolution among patients with colorectal cancer-related abnormalities. J Cancer Educ 29:144-50
Wells, Kristen J; Arevalo, Mariana; Meade, Cathy D et al. (2014) Development and validation of the biobanking attitudes and knowledge survey (BANKS). Cancer Epidemiol Biomarkers Prev 23:374-82
Lee, Ji-Hyun; Fulp, William; Wells, Kristen J et al. (2013) Patient navigation and time to diagnostic resolution: results for a cluster randomized trial evaluating the efficacy of patient navigation among patients with breast cancer screening abnormalities, Tampa, FL. PLoS One 8:e74542
Quinn, Gwendolyn P; Castaneda, Heide; Pal, Tuya et al. (2013) Risk terminology in biobanking and genetic research: what's in a name? Am J Med Genet A 161A:2095-8