The specific aims of the Biorepository Shared Resource are (1) to facilitate the TREC Center research projects by providing expertise and centralized service in the collection, processing, analysis and management of biological samples, and (2) to serve as a source of biological samples for ancillary and future studies during and beyond the TREC Center operation, because biological samples may be made available for use in research as new knowledge in this area evolves. The core faculty and staff also will provide expert guidance into final selection of assays and laboratories for TREC Center project biological sample analysis, ensuring that analytical laboratories are monitored for quality control (QC) data and activities. The core personnel, who have specialized training and expertise, will facilitate appropriate biological sample collection and processing methods, materials, and procedures to ensure that the data and results produced by TREC Center projects are of good quality to enable the aims to be optimally addressed. A key component ofthe Biorepository Shared Resource is a computer-based system to log and track all samples and aliquots, so that analyses of TREC Center projects are efficient and the likelihood of misplaced samples and missing data is minimized. Core personnel will use equipment and instrumentation that is high-quality, and well-maintained. Providing the materials and services necessary for biological sample collection and management through a centralized core will ensure quality and efficiency for the TREC Center research projects.
|Hartman, Sheri J; Marinac, Catherine R; Natarajan, Loki et al. (2015) Lifestyle factors associated with cognitive functioning in breast cancer survivors. Psychooncology 24:669-75|
|Chung, H; Lee, Y S; Mayoral, R et al. (2015) Omega-3 fatty acids reduce obesity-induced tumor progression independent of GPR120 in a mouse model of postmenopausal breast cancer. Oncogene 34:3504-13|
|Emond, Jennifer A; Pierce, John P; Natarajan, Loki et al. (2014) Risk of breast cancer recurrence associated with carbohydrate intake and tissue expression of IGFI receptor. Cancer Epidemiol Biomarkers Prev 23:1273-9|
|James, Peter; Berrigan, David; Hart, Jaime E et al. (2014) Effects of buffer size and shape on associations between the built environment and energy balance. Health Place 27:162-70|
|Patterson, Ruth E; Rock, Cheryl L; Kerr, Jacqueline et al. (2013) Metabolism and breast cancer risk: frontiers in research and practice. J Acad Nutr Diet 113:288-96|
|Schmitz, Kathryn H; Neuhouser, Marian L; Agurs-Collins, Tanya et al. (2013) Impact of obesity on cancer survivorship and the potential relevance of race and ethnicity. J Natl Cancer Inst 105:1344-54|