? Pilot Projects One pilot project will be funded per year, beginning in Year 2 of the award. The purpose of these projects will be to conduct translational research in Barrett's esophagus that meets the objectives of the BETRNet, falls within one of the four designated Research Areas, and that can utilize effectively the resources available through our integrated Research Center. Cross-BETRNet Activities One Cross-BETRNet project will be funded per year, beginning in Year 2 of the award. The purpose of these projects will be to conduct translational research in Barrett's esophagus that meets the objectives of the BETRNet, falls within one of the four designated Research Areas, and that can feasibly utilize the resources available through our Research Center in combination with the other BETRNet consortia. The below outlined application details will be modified as needed based on guidelines set forth by the BETRNet Steering Committee. In order to minimize duplicated effort, much of the organization, administration, and oversight for Cross-BETRNet Projects is similar to that described above for the Pilot Projects. Additionally, we have commitment from other BETRNet Consortium applicants regarding potential future cross-BETRNet collaborative efforts (see Section 2.7. Letters of Commitment).

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA163004-02
Application #
8409831
Study Section
Special Emphasis Panel (ZCA1-SRLB-1)
Project Start
Project End
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
2
Fiscal Year
2012
Total Cost
$185,173
Indirect Cost
$52,615
Name
Columbia University (N.Y.)
Department
Type
DUNS #
621889815
City
New York
State
NY
Country
United States
Zip Code
10032
Fecteau, Ryan E; Kong, Jianping; Kresak, Adam et al. (2016) Association Between Germline Mutation in VSIG10L and Familial Barrett Neoplasia. JAMA Oncol 2:1333-1339
Critchley-Thorne, Rebecca J; Duits, Lucas C; Prichard, Jeffrey W et al. (2016) A Tissue Systems Pathology Assay for High-Risk Barrett's Esophagus. Cancer Epidemiol Biomarkers Prev 25:958-68
Bansal, Ajay; Gupta, Vijayalaxmi; Wang, Kenneth (2016) MicroRNA Expression Signatures During Malignant Progression From Barrett's Esophagus. J Cell Biochem 117:1288-95
Chan, Daniel K; Leggett, Cadman L; Wang, Kenneth K (2016) Diagnosing gastrointestinal illnesses using fecal headspace volatile organic compounds. World J Gastroenterol 22:1639-49
Schellnegger, Raphael; Quante, Anne; Rospleszcz, Susanne et al. (2016) Goblet Cell Ratio in Combination with Differentiation and Stem Cell Markers in Barrett Esophagus Allow Distinction of Patients with and without Esophageal Adenocarcinoma. Cancer Prev Res (Phila) :
Kong, Jianping; Whelan, Kelly A; Laczkó, Dorottya et al. (2016) Autophagy levels are elevated in barrett's esophagus and promote cell survival from acid and oxidative stress. Mol Carcinog 55:1526-1541
Snider, Erik J; Freedberg, Daniel E; Abrams, Julian A (2016) Potential Role of the Microbiome in Barrett's Esophagus and Esophageal Adenocarcinoma. Dig Dis Sci 61:2217-25
Pattison, Amanda M; Blomain, Erik S; Merlino, Dante J et al. (2016) Intestinal Enteroids Model Guanylate Cyclase C-Dependent Secretion Induced by Heat-Stable Enterotoxins. Infect Immun 84:3083-91
Small, Aaron J; Sutherland, Scott E; Hightower, Jessica S et al. (2015) Comparative risk of recurrence of dysplasia and carcinoma after endoluminal eradication therapy of high-grade dysplasia versus intramucosal carcinoma in Barrett's esophagus. Gastrointest Endosc 81:1158-66.e1-4
Stachler, Matthew D; Taylor-Weiner, Amaro; Peng, Shouyong et al. (2015) Paired exome analysis of Barrett's esophagus and adenocarcinoma. Nat Genet 47:1047-55

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