? Pilot Projects One pilot project will be funded per year, beginning in Year 2 of the award. The purpose of these projects will be to conduct translational research in Barrett's esophagus that meets the objectives of the BETRNet, falls within one of the four designated Research Areas, and that can utilize effectively the resources available through our integrated Research Center. Cross-BETRNet Activities One Cross-BETRNet project will be funded per year, beginning in Year 2 of the award. The purpose of these projects will be to conduct translational research in Barrett's esophagus that meets the objectives of the BETRNet, falls within one of the four designated Research Areas, and that can feasibly utilize the resources available through our Research Center in combination with the other BETRNet consortia. The below outlined application details will be modified as needed based on guidelines set forth by the BETRNet Steering Committee. In order to minimize duplicated effort, much of the organization, administration, and oversight for Cross-BETRNet Projects is similar to that described above for the Pilot Projects. Additionally, we have commitment from other BETRNet Consortium applicants regarding potential future cross-BETRNet collaborative efforts (see Section 2.7. Letters of Commitment).

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA163004-04
Application #
8731835
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
4
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
Kasagi, Yuta; Chandramouleeswaran, Prasanna M; Whelan, Kelly A et al. (2018) The Esophageal Organoid System Reveals Functional Interplay Between Notch and Cytokines in Reactive Epithelial Changes. Cell Mol Gastroenterol Hepatol 5:333-352
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