Adult brain cancer continues to be a significant challenge to clinicians and over 20,000 cases are diagnosed per year. Because the prognosis for individuals with glioblastoma, the most common type of brain cancer, remains poor, it is of critical importance that new therapies be developed. This proposal requests funds to support a research program that integrates physical sciences concepts and approaches with basic and clinical cancer biology research strategies to explore the role of cell intrinsic and external force in GBM aggression. The hope is that this interdisciplinary approach will offer a new paradigm with which to clarify the basis for the invasive and treatment resistant phenotype of high grade GBMs, and by so doing reveal new avenues for developing novel diagnostics, prognostics and therapies.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA163155-03
Application #
8741085
Study Section
Special Emphasis Panel (ZCA1-SRLB-3 (O1))
Project Start
2011-09-26
Project End
2016-07-31
Budget Start
2013-08-01
Budget End
2014-07-31
Support Year
3
Fiscal Year
2013
Total Cost
$109,913
Indirect Cost
$38,879
Name
University of California San Francisco
Department
Type
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
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