The National Alliance for Medical Imaging Computing (NAMIC) is a multiinstitutional, interdisciplinary team of computer scientists, software engineers, and medical investigators who develop computational tools for the analysis and visualization of medical image data. The purpose of the center is to provide the infrastructure and environment for the development of computational algorithms and open source technologies, and then oversee the training and dissemination of these tools to the medical research community. This world-class software and development environment serves as a foundation for accelerating the development and deployment of computational tools that are readily accessible to the medical research community. The team combines cutting-edge computer vision research (to create medical imaging analysis algorithms) with state of the art software engineering techniques (based on """"""""extreme"""""""" programming techniques in a distributed, open-source environment) to enable computational examination of both basic neurosience and neurologicat disorders. In developing this infrastructure resource, the team will significantly expand upon proven open systems technology and platforms. The driving biological projects will come initially from the study of schizophrenia, but the methods will be applicable to many other diseases. The computational tools and open systems technologies and platforms developed by NAMIC will initially be used to study anatomical structures and connectivity patterns in the brain, derangements of which have long been thought to play a role in the etiology of schizophrenia. The overall analysis will occur at a range of scales, and will occur across a range of modalities including diffusion MRI, quantitative EGG, and metabolic and receptor PET, but potentially including microscopic, genomic, and other image data. It will apply to image data from individual )atients,and to studies executed across large poplulations. The data will be taken from subjects across a Nide range of time scales and ultimately apply to a broad range of diseases in a broad range of organs.

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
3U54EB005149-05S4
Application #
7915998
Study Section
Special Emphasis Panel (ZRG1-BST-A (55))
Program Officer
Pai, Vinay Manjunath
Project Start
2004-09-17
Project End
2010-09-29
Budget Start
2008-08-01
Budget End
2010-09-29
Support Year
5
Fiscal Year
2009
Total Cost
$3,720,664
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
02115
Ghayoor, Ali; Vaidya, Jatin G; Johnson, Hans J (2018) Robust automated constellation-based landmark detection in human brain imaging. Neuroimage 170:471-481
Wachinger, Christian; Toews, Matthew; Langs, Georg et al. (2018) Keypoint Transfer for Fast Whole-Body Segmentation. IEEE Trans Med Imaging :
Lyu, Ilwoo; Perdomo, Jonathan; Yapuncich, Gabriel S et al. (2018) Group-wise Shape Correspondence of Variable and Complex Objects. Proc SPIE Int Soc Opt Eng 10574:
Hong, Sungmin; Fishbaugh, James; Gerig, Guido (2018) 4D CONTINUOUS MEDIAL REPRESENTATION BY GEODESIC SHAPE REGRESSION. Proc IEEE Int Symp Biomed Imaging 2018:1014-1017
Swanson, Meghan R; Wolff, Jason J; Shen, Mark D et al. (2018) Development of White Matter Circuitry in Infants With Fragile X Syndrome. JAMA Psychiatry 75:505-513
Swanson, Meghan R; Shen, Mark D; Wolff, Jason J et al. (2018) Naturalistic Language Recordings Reveal ""Hypervocal"" Infants at High Familial Risk for Autism. Child Dev 89:e60-e73
Swanson, Meghan R; Shen, Mark D; Wolff, Jason J et al. (2017) Subcortical Brain and Behavior Phenotypes Differentiate Infants With Autism Versus Language Delay. Biol Psychiatry Cogn Neurosci Neuroimaging 2:664-672
Veni, Gopalkrishna; Elhabian, Shireen Y; Whitaker, Ross T (2017) ShapeCut: Bayesian surface estimation using shape-driven graph. Med Image Anal 40:11-29
Irimia, Andrei; Goh, Sheng-Yang Matthew; Wade, Adam C et al. (2017) Traumatic Brain Injury Severity, Neuropathophysiology, and Clinical Outcome: Insights from Multimodal Neuroimaging. Front Neurol 8:530
Rutherford, Helena J V; Maupin, Angela N; Landi, Nicole et al. (2017) Parental reflective functioning and the neural correlates of processing infant affective cues. Soc Neurosci 12:519-529

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