The project in adaptive radiotherapy (RT) at Massachusetts General Hospital requires the quantification of change in body systems during disease progression and management to guide the application of radiation to tumor volumes while sparing critical structures. Segmentation and registration of serial CT datasets and interaction with commercial treatment planning systems will be used to determine best practices for radiotherapy, in general, with a particular benefit anticipated for proton therapy.

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54EB005149-08
Application #
8377482
Study Section
Special Emphasis Panel (ZRG1-BST-K)
Project Start
Project End
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
8
Fiscal Year
2012
Total Cost
$257,891
Indirect Cost
$977
Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
02115
Wachinger, Christian; Brennan, Matthew; Sharp, Greg C et al. (2017) Efficient Descriptor-Based Segmentation of Parotid Glands With Nonlocal Means. IEEE Trans Biomed Eng 64:1492-1502
Norton, Isaiah; Essayed, Walid Ibn; Zhang, Fan et al. (2017) SlicerDMRI: Open Source Diffusion MRI Software for Brain Cancer Research. Cancer Res 77:e101-e103
Sadeghi, Neda; Gilmore, John H; Gerig, Guido (2017) Twin-singleton developmental study of brain white matter anatomy. Hum Brain Mapp 38:1009-1024
Veni, Gopalkrishna; Elhabian, Shireen Y; Whitaker, Ross T (2017) ShapeCut: Bayesian surface estimation using shape-driven graph. Med Image Anal 40:11-29
Irimia, Andrei; Goh, Sheng-Yang Matthew; Wade, Adam C et al. (2017) Traumatic Brain Injury Severity, Neuropathophysiology, and Clinical Outcome: Insights from Multimodal Neuroimaging. Front Neurol 8:530
Ghayoor, Ali; Vaidya, Jatin G; Johnson, Hans J (2017) Robust automated constellation-based landmark detection in human brain imaging. Neuroimage :
Swanson, Meghan R; Wolff, Jason J; Elison, Jed T et al. (2017) Splenium development and early spoken language in human infants. Dev Sci 20:
Hong, Sungmin; Fishbaugh, James; Rezanejad, Morteza et al. (2017) Subject-Specific Longitudinal Shape Analysis by Coupling Spatiotemporal Shape Modeling with Medial Analysis. Proc SPIE Int Soc Opt Eng 10133:
Wolff, Jason J; Swanson, Meghan R; Elison, Jed T et al. (2017) Neural circuitry at age 6 months associated with later repetitive behavior and sensory responsiveness in autism. Mol Autism 8:8
Hazlett, Heather Cody; Gu, Hongbin; Munsell, Brent C et al. (2017) Early brain development in infants at high risk for autism spectrum disorder. Nature 542:348-351

Showing the most recent 10 out of 652 publications