Current neuroimaging technologies are not able to detect neuroanatomical changes in individuals suffering from trauma or other pathology, because current methods rely on spatial normalization across subjects. However, longitudinal imaging allows patients to serve as their own controls and removes the need for inter-subject spatial alignment. The collaboration with UCLA to study traumatic brain injury (TBI) will take advantage of longitudinal imaging analysis by delivering customized analysis pipelines that are robust in the presence of the case-specific imaging signatures of head trauma. These pipelines promise to reveal previously hidden consequences of TBI to inform clinical decision-making.

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54EB005149-09
Application #
8501014
Study Section
Special Emphasis Panel (ZRG1-BST-K)
Project Start
Project End
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
9
Fiscal Year
2013
Total Cost
$209,873
Indirect Cost
$1,017
Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
02115
Ghayoor, Ali; Vaidya, Jatin G; Johnson, Hans J (2018) Robust automated constellation-based landmark detection in human brain imaging. Neuroimage 170:471-481
Wachinger, Christian; Toews, Matthew; Langs, Georg et al. (2018) Keypoint Transfer for Fast Whole-Body Segmentation. IEEE Trans Med Imaging :
Lyu, Ilwoo; Perdomo, Jonathan; Yapuncich, Gabriel S et al. (2018) Group-wise Shape Correspondence of Variable and Complex Objects. Proc SPIE Int Soc Opt Eng 10574:
Hong, Sungmin; Fishbaugh, James; Gerig, Guido (2018) 4D CONTINUOUS MEDIAL REPRESENTATION BY GEODESIC SHAPE REGRESSION. Proc IEEE Int Symp Biomed Imaging 2018:1014-1017
Swanson, Meghan R; Wolff, Jason J; Shen, Mark D et al. (2018) Development of White Matter Circuitry in Infants With Fragile X Syndrome. JAMA Psychiatry 75:505-513
Swanson, Meghan R; Shen, Mark D; Wolff, Jason J et al. (2018) Naturalistic Language Recordings Reveal ""Hypervocal"" Infants at High Familial Risk for Autism. Child Dev 89:e60-e73
Swanson, Meghan R; Shen, Mark D; Wolff, Jason J et al. (2017) Subcortical Brain and Behavior Phenotypes Differentiate Infants With Autism Versus Language Delay. Biol Psychiatry Cogn Neurosci Neuroimaging 2:664-672
Veni, Gopalkrishna; Elhabian, Shireen Y; Whitaker, Ross T (2017) ShapeCut: Bayesian surface estimation using shape-driven graph. Med Image Anal 40:11-29
Irimia, Andrei; Goh, Sheng-Yang Matthew; Wade, Adam C et al. (2017) Traumatic Brain Injury Severity, Neuropathophysiology, and Clinical Outcome: Insights from Multimodal Neuroimaging. Front Neurol 8:530
Rutherford, Helena J V; Maupin, Angela N; Landi, Nicole et al. (2017) Parental reflective functioning and the neural correlates of processing infant affective cues. Soc Neurosci 12:519-529

Showing the most recent 10 out of 668 publications