The Point-of-Care Center for Emerging Neuro Technologies (POC-CENT) is focused on developing diagnostic technologies for neurologic emergencies where information is needed by the physician quickly. The remit for the technologies to be developed is to advance point-of-care information and information flow for the neurologic patient in the emergency room, neurosurgery suite, for neuroradiology and the neurosurgical intensive care unit. Indeed anytime the physician requires rapid information from the neurologic patient it will be considered as having potential need for point-of-care diagnostic information. This will include but not be limited to: blood tests, urinalysis, imaging, non-invasive sensors, spinal fluid, and biopsy / tissue samples. In the POC-CENT, there are 5 cores representing numerous disciplines to foster and facilitate taking ideas and applying them to clinical applications. These cores are: 1) Clinical testing, 2) Exploratory projects 3) Clinical Needs Assessment, 4) Training and 5) Administration. Supporting these cores we have representatives from Neurology, Neurosurgery, Engineering, Entrepreneurial Development, The Business Community, The Medical Device Industry and University Administration. A strength of the University of Cincinnati and the Cincinnati community is that we currently do all of these cores for our life sciences community. We have multiple incubators for companies, strong clinical trials experience, a wealth of training and funding opportunities for all stages of technology development. Indeed there will be an opportunity to partner with other funding agencies locally to add value to the technologies that enter into our program. Our team's goal is to improve the care and health of the neurologic patients by providing fast and reliable information about the biolocal event they are experiencing. We will achieve this goal by developing a pipeline of technologies and a pathway to develop emerging neuro technologies focused on point-of-care diagnostics. Further, we will work closely in the region and with the POCT Research Network to accomplish our goals. We are fortunate to have an engineering, medical, scientific and commercial community that already works well together and can be facilitated to do all the aspects of this project as part of the POCT Research Network.

National Institute of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Specialized Center--Cooperative Agreements (U54)
Project #
Application #
Study Section
Special Emphasis Panel (ZEB1-OSR-D (O1))
Program Officer
Korte, Brenda
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Cincinnati
Engineering (All Types)
Schools of Engineering
United States
Zip Code
Esenaliev, Rinat O (2017) Optoacoustic Monitoring of Physiologic Variables. Front Physiol 8:1030
Esenaliev, Rinat O (2017) Optoacoustic diagnostic modality: from idea to clinical studies with highly compact laser diode-based systems. J Biomed Opt 22:91512
Atefi, Seyed Reza; Seoane, Fernando; Kamalian, Shervin et al. (2016) Intracranial hemorrhage alters scalp potential distribution in bioimpedance cerebral monitoring: Preliminary results from FEM simulation on a realistic head model and human subjects. Med Phys 43:675-86
Subbian, Vignesh; Ratcliff, Jonathan J; Korfhagen, Joseph J et al. (2016) A Novel Tool for Evaluation of Mild Traumatic Brain Injury Patients in the Emergency Department: Does Robotic Assessment of Neuromotor Performance Following Injury Predict the Presence of Postconcussion Symptoms at Follow-up? Acad Emerg Med 23:382-92
Bick, Sarah K B; Izzy, Saef; Rubin, Daniel B et al. (2016) Anterior Temporal Lobectomy for Refractory Status Epilepticus in Herpes Simplex Encephalitis. Neurocrit Care 25:458-463
Jia, Wenyan; Wu, Jiamin; Gao, Di et al. (2016) Visualization of electrical field of electrode using voltage-controlled fluorescence release. Comput Biol Med 75:38-44
Struck, Aaron F; Westover, M Brandon; Hall, Lance T et al. (2016) Metabolic Correlates of the Ictal-Interictal Continuum: FDG-PET During Continuous EEG. Neurocrit Care 24:324-31
Clark, Joseph F; Colosimo, Angelo; Ellis, James K et al. (2015) Vision training methods for sports concussion mitigation and management. J Vis Exp :e52648
Luan, Bo; Sun, Mingui (2015) A Simulation Study on a Single-Unit Wireless EEG Sensor. Proc IEEE Annu Northeast Bioeng Conf 2015:
Subbian, Vignesh; Ratcliff, Jonathan J; Meunier, Jason M et al. (2015) Integration of New Technology for Research in the Emergency Department: Feasibility of Deploying a Robotic Assessment Tool for Mild Traumatic Brain Injury Evaluation. IEEE J Transl Eng Health Med 3:3200109

Showing the most recent 10 out of 36 publications