Administrative Core (AC). The AC is responsible for monitoring scientific progress and production, communicating decisions and priorities of the SC to the Cores, dissemination of information internally, to collaborators, NIGMS, SBPs, and the scientific community (via the Web + Publications), and integration among Cores. The AC hosts the monthly SC meetings, and weekly management and operations teleconferences, chaired by AC manager, Marc Elsliger. The AC continues to maintain Windows Database and Linux Servers for communication and transfer of data between the TSRI-CC, GNF-CC and the Central JCSG DB, and relies primarily on standard off the shelve software solutions with a robust database backend and is closely linked to the BIC informatics group at UCSD. This environment provides industry standard productivity tools for management and administration of the JCSG as a heterogeneous, multi-institutional center. This centralized resource includes email, scheduling and calendaring support via an MS Exchange Server, a document exchange portal for all JCSG staff members and JCSG collaborators through a web-based SharePoint portal, and storage is provided on each server in a RAID5 configuration. Resources are re-evaluated annually.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Specialized Center--Cooperative Agreements (U54)
Project #
Application #
Study Section
Special Emphasis Panel (ZGM1-CBB-4)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Scripps Research Institute
La Jolla
United States
Zip Code
Roncase, Emily J; Moon, Clara; Chatterjee, Sandip et al. (2017) Substrate Profiling and High Resolution Co-complex Crystal Structure of a Secreted C11 Protease Conserved across Commensal Bacteria. ACS Chem Biol 12:1556-1565
Guenaga, Javier; Garces, Fernando; de Val, Natalia et al. (2017) Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein. Immunity 46:792-803.e3
Tzarum, Netanel; McBride, Ryan; Nycholat, Corwin M et al. (2017) Unique Structural Features of Influenza Virus H15 Hemagglutinin. J Virol 91:
Gopal, Radhika; Jackson, Kelli; Tzarum, Netanel et al. (2017) Probing the antigenicity of hepatitis C virus envelope glycoprotein complex by high-throughput mutagenesis. PLoS Pathog 13:e1006735
Tzarum, Netanel; de Vries, Robert P; Peng, Wenjie et al. (2017) The 150-Loop Restricts the Host Specificity of Human H10N8 Influenza Virus. Cell Rep 19:235-245
McLuskey, Karen; Grewal, Jaspreet S; Das, Debanu et al. (2016) Crystal Structure and Activity Studies of the C11 Cysteine Peptidase from Parabacteroides merdae in the Human Gut Microbiome. J Biol Chem 291:9482-91
Kong, Leopold; Lee, David E; Kadam, Rameshwar U et al. (2016) Structural flexibility at a major conserved antibody target on hepatitis C virus E2 antigen. Proc Natl Acad Sci U S A :
Xu, Qingping; Shoji, Mikio; Shibata, Satoshi et al. (2016) A Distinct Type of Pilus from the Human Microbiome. Cell 165:690-703
Serrano, Pedro; Dutta, Samit K; Proudfoot, Andrew et al. (2016) NMR in structural genomics to increase structural coverage of the protein universe: Delivered by Prof. Kurt W├╝thrich on 7 July 2013 at the 38th FEBS Congress in St. Petersburg, Russia. FEBS J 283:3870-3881
Proudfoot, Andrew; Geralt, Michael; Elsliger, Marc-Andre et al. (2016) Dynamic Local Polymorphisms in the Gbx1 Homeodomain Induced by DNA Binding. Structure 24:1372-1379

Showing the most recent 10 out of 128 publications