Administrative Core (AC). The AC is responsible for monitoring scientific progress and production, communicating decisions and priorities of the SC to the Cores, dissemination of information internally, to collaborators, NIGMS, SBPs, and the scientific community (via the Web + Publications), and integration among Cores. The AC hosts the monthly SC meetings, and weekly management and operations teleconferences, chaired by AC manager, Marc Elsliger. The AC continues to maintain Windows Database and Linux Servers for communication and transfer of data between the TSRI-CC, GNF-CC and the Central JCSG DB, and relies primarily on standard off the shelve software solutions with a robust database backend and is closely linked to the BIC informatics group at UCSD. This environment provides industry standard productivity tools for management and administration of the JCSG as a heterogeneous, multi-institutional center. This centralized resource includes email, scheduling and calendaring support via an MS Exchange Server, a document exchange portal for all JCSG staff members and JCSG collaborators through a web-based SharePoint portal, and storage is provided on each server in a RAID5 configuration. Resources are re-evaluated annually.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54GM094586-05
Application #
8692874
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
5
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
(2018) Retraction: Site?specific recombination of nitrogen?fixation genes in cyanobacteria by XisF–XisH–XisI complex: Structures and models, William C. Hwang, James W. Golden, Jaime Pascual, Dong Xu, Anton Cheltsov, Adam Godzik Proteins 86:268
Serrano, Pedro; Hammond, John A; Geralt, Michael et al. (2018) Splicing Site Recognition by Synergy of Three Domains in Splicing Factor RBM10. Biochemistry 57:1563-1567
Tzarum, Netanel; McBride, Ryan; Nycholat, Corwin M et al. (2017) Unique Structural Features of Influenza Virus H15 Hemagglutinin. J Virol 91:
Gopal, Radhika; Jackson, Kelli; Tzarum, Netanel et al. (2017) Probing the antigenicity of hepatitis C virus envelope glycoprotein complex by high-throughput mutagenesis. PLoS Pathog 13:e1006735
Guenaga, Javier; Garces, Fernando; de Val, Natalia et al. (2017) Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein. Immunity 46:792-803.e3
Tzarum, Netanel; de Vries, Robert P; Peng, Wenjie et al. (2017) The 150-Loop Restricts the Host Specificity of Human H10N8 Influenza Virus. Cell Rep 19:235-245
Roncase, Emily J; Moon, Clara; Chatterjee, Sandip et al. (2017) Substrate Profiling and High Resolution Co-complex Crystal Structure of a Secreted C11 Protease Conserved across Commensal Bacteria. ACS Chem Biol 12:1556-1565
McLuskey, Karen; Grewal, Jaspreet S; Das, Debanu et al. (2016) Crystal Structure and Activity Studies of the C11 Cysteine Peptidase from Parabacteroides merdae in the Human Gut Microbiome. J Biol Chem 291:9482-91
Kong, Leopold; Lee, David E; Kadam, Rameshwar U et al. (2016) Structural flexibility at a major conserved antibody target on hepatitis C virus E2 antigen. Proc Natl Acad Sci U S A 113:12768-12773
Kong, Leopold; He, Linling; de Val, Natalia et al. (2016) Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability. Nat Commun 7:12040

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