Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54GM094610-05
Application #
8715820
Study Section
Special Emphasis Panel (ZGM1-CBB-3)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
5
Fiscal Year
2014
Total Cost
$510,468
Indirect Cost
$56,996
Name
California Institute of Technology
Department
Type
DUNS #
009584210
City
Pasadena
State
CA
Country
United States
Zip Code
91125
He, Xiao; Garza, Denisse; Nigam, Sanjay K et al. (2016) Multispecific Organic Cation Transporter 1 (OCT1) from Bos taurus Has High Affinity and Slow Binding Kinetics towards Prostaglandin E2. PLoS One 11:e0152969
Vastermark, Ake; Driker, Adelle; Weng, Jingwei et al. (2016) The V-motifs facilitate the substrate capturing step of the PTS elevator mechanism. J Struct Biol 196:496-502
Hildebrandt, Ellen; Ding, Haitao; Mulky, Alok et al. (2015) A stable human-cell system overexpressing cystic fibrosis transmembrane conductance regulator recombinant protein at the cell surface. Mol Biotechnol 57:391-405
Saier Jr, Milton H (2015) The Bacterial Phosphotransferase System: New Frontiers 50 Years after Its Discovery. J Mol Microbiol Biotechnol 25:73-8
Moeller, Arne; Lee, Sung Chang; Tao, Houchao et al. (2015) Distinct conformational spectrum of homologous multidrug ABC transporters. Structure 23:450-60
Babbitt, Patricia C; Bagos, Pantelis G; Bairoch, Amos et al. (2015) Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat. Database (Oxford) 2015:bav063
Västermark, Åke; Driker, Adelle; Li, Jiaqi et al. (2015) Conserved movement of TMS11 between occluded conformations of LacY and XylE of the major facilitator superfamily suggests a similar hinge-like mechanism. Proteins 83:735-45
Västermark, Ake; Saier Jr, Milton H (2014) The involvement of transport proteins in transcriptional and metabolic regulation. Curr Opin Microbiol 18:8-15
Swartz, Douglas J; Mok, Leo; Botta, Sri K et al. (2014) Directed evolution of P-glycoprotein cysteines reveals site-specific, non-conservative substitutions that preserve multidrug resistance. Biosci Rep 34:
Västermark, Ake; Lunt, Bryan; Saier, Milton (2014) Major facilitator superfamily porters, LacY, FucP and XylE of Escherichia coli appear to have evolved positionally dissimilar catalytic residues without rearrangement of 3-TMS repeat units. J Mol Microbiol Biotechnol 24:82-90

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