Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54GM094625-03
Application #
8380617
Study Section
Special Emphasis Panel (ZGM1-CBB-3)
Project Start
Project End
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
3
Fiscal Year
2012
Total Cost
$170,600
Indirect Cost
$94,564
Name
University of California San Francisco
Department
Type
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Metcalf, Brian; Chuang, Chihyuan; Dufu, Kobina et al. (2017) Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin. ACS Med Chem Lett 8:321-326
Webb, Benjamin; Sali, Andrej (2017) Protein Structure Modeling with MODELLER. Methods Mol Biol 1654:39-54
Dang, Bobo; Wu, Haifan; Mulligan, Vikram Khipple et al. (2017) De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures. Proc Natl Acad Sci U S A 114:10852-10857
Li, Zhe; Partridge, James; Silva-Garcia, Abel et al. (2017) Structure-Guided Design of Novel, Potent, and Selective Macrocyclic Plasma Kallikrein Inhibitors. ACS Med Chem Lett 8:185-190
Martin-Garcia, Jose M; Conrad, Chelsie E; Coe, Jesse et al. (2016) Serial femtosecond crystallography: A revolution in structural biology. Arch Biochem Biophys 602:32-47
Arrigoni, Cristina; Rohaim, Ahmed; Shaya, David et al. (2016) Unfolding of a Temperature-Sensitive Domain Controls Voltage-Gated Channel Activation. Cell 164:922-36
Kessans, Sarah A; Linhart, Mark D; Meador, Lydia R et al. (2016) Immunological Characterization of Plant-Based HIV-1 Gag/Dgp41 Virus-Like Particles. PLoS One 11:e0151842
Schumacher, Maria A; Lee, Jeehyun; Zeng, Wenjie (2016) Molecular insights into DNA binding and anchoring by the Bacillus subtilis sporulation kinetochore-like RacA protein. Nucleic Acids Res 44:5438-49
Poncet-Montange, Guillaume; Zhan, Yanai; Bardenhagen, Jennifer P et al. (2015) Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2. Biochem J 466:337-46
Rosenberg, Oren S; Dovala, Dustin; Li, Xueming et al. (2015) Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion. Cell 161:501-512

Showing the most recent 10 out of 54 publications