Abstract

The primary goal of the Administrative Core is to manage all reporting, regulatory, financial, logistic, and administrative matters of the Center for HIV-1RNA Studies, as well as foster collaborations and scientifically enriching experiences, thereby providing CRNA investigators an environment in which they can put science first to the fullest extent possible. The Administrative Core is located at the University of Michigan and led by Program Director Alice Telesnitsky, in consultation with the CRNA Executive Committee (EC), composed of structural biologists Janet Smith and Mike Summers, and virologists Alice Telesnitsky and Paul Bieniasz. The overall aims of the Admin Core are Aim I: CRNA Management: To establish and maintain an effective management plan that supports the projects, scientific output, and personnel of the CRNA.
Aim II : Collaborative Development: To support and manage a vigorous collaborative development plan, through which scientists outside the core CRNA membership can contribute to and benefit from the CRNA.
Aim III : Education and Outreach: To facilitate and promote interactions with be broader scientific community, and to provide outreach and educational training opportunities.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54GM103297-07
Application #
9557499
Study Section
Special Emphasis Panel (ZRG1)
Project Start
Project End
Budget Start
2018-09-01
Budget End
2019-08-31
Support Year
7
Fiscal Year
2018
Total Cost
Indirect Cost

  Institution

Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109

  Publications

Shi, Honglue; Clay, Mary C; Rangadurai, Atul et al. (2018) Atomic structures of excited state A-T Hoogsteen base pairs in duplex DNA by combining NMR relaxation dispersion, mutagenesis, and chemical shift calculations. J Biomol NMR 70:229-244
Kraus, Jodi; Gupta, Rupal; Yehl, Jenna et al. (2018) Chemical Shifts of the Carbohydrate Binding Domain of Galectin-3 from Magic Angle Spinning NMR and Hybrid Quantum Mechanics/Molecular Mechanics Calculations. J Phys Chem B 122:2931-2939
Marchant, Jan; Bax, Ad; Summers, Michael F (2018) Accurate Measurement of Residual Dipolar Couplings in Large RNAs by Variable Flip Angle NMR. J Am Chem Soc 140:6978-6983
Dick, Robert A; Zadrozny, Kaneil K; Xu, Chaoyi et al. (2018) Inositol phosphates are assembly co-factors for HIV-1. Nature 560:509-512
Patwardhan, Neeraj N; Cai, Zhengguo; Newson, Colby N et al. (2018) Fluorescent peptide displacement as a general assay for screening small molecule libraries against RNA. Org Biomol Chem :
Levengood, Jeffrey D; Tolbert, Blanton S (2018) Idiosyncrasies of hnRNP A1-RNA recognition: Can binding mode influence function. Semin Cell Dev Biol :
Zhang, Kaiming; Keane, Sarah C; Su, Zhaoming et al. (2018) Structure of the 30 kDa HIV-1 RNA Dimerization Signal by a Hybrid Cryo-EM, NMR, and Molecular Dynamics Approach. Structure 26:490-498.e3
Takata, Matthew A; Soll, Steven J; Emery, Ann et al. (2018) Global synonymous mutagenesis identifies cis-acting RNA elements that regulate HIV-1 splicing and replication. PLoS Pathog 14:e1006824
Bieniasz, Paul D; Kutluay, Sebla B (2018) CLIP-related methodologies and their application to retrovirology. Retrovirology 15:35
Hron, Tomáš; Farkašová, Helena; Gifford, Robert J et al. (2018) Remnants of an Ancient Deltaretrovirus in the Genomes of Horseshoe Bats (Rhinolophidae). Viruses 10:

Showing the most recent 10 out of 15 publications