The Cell and Tissue Culture Core laboratory is designed to provide state-of-the-art tissue and cell culture facilities to the individual projects of the Center for Reproductive Biological Research. This Core will perform in vitro culture of immortilized and primary mammalian cells, murine embryonic stem cell manipulations and lentivirus and adenovirus production, as required by Center investigators and their staff. In addition, this facility will train Core users in the use of in vitro cell culture technologies. A combination of a common, well-equipped tissue culture facility and centralized purchasing of standard and specialized cell culture reagents directly benefits individual projects by improving reproducibility, time utilization and cost management.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54HD007495-40
Application #
8446127
Study Section
Special Emphasis Panel (ZHD1-DSR-L)
Project Start
Project End
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
40
Fiscal Year
2013
Total Cost
$147,783
Indirect Cost
$64,086
Name
Baylor College of Medicine
Department
Type
DUNS #
051113330
City
Houston
State
TX
Country
United States
Zip Code
77030
Han, Sang Jun; O'Malley, Bert W (2014) The dynamics of nuclear receptors and nuclear receptor coregulators in the pathogenesis of endometriosis. Hum Reprod Update 20:467-84
Lee, Jae Man; Wagner, Martin; Xiao, Rui et al. (2014) Nutrient-sensing nuclear receptors coordinate autophagy. Nature 516:112-5
Zhang, Yin-Li; Xia, Yan; Yu, Chao et al. (2014) CBP-CITED4 is required for luteinizing hormone-triggered target gene expression during ovulation. Mol Hum Reprod 20:850-60
Wetendorf, Margeaux; DeMayo, Francesco J (2014) Progesterone receptor signaling in the initiation of pregnancy and preservation of a healthy uterus. Int J Dev Biol 58:95-106
Stossi, Fabio; Bolt, Michael J; Ashcroft, Felicity J et al. (2014) Defining estrogenic mechanisms of bisphenol A analogs through high throughput microscopy-based contextual assays. Chem Biol 21:743-53
Cerne, Jasmina Ziva; Hartig, Sean Michael; Hamilton, Mark Patrick et al. (2014) Protein kinase C inhibitors sensitize GNAQ mutant uveal melanoma cells to ionizing radiation. Invest Ophthalmol Vis Sci 55:2130-9
Kim, Tae Hoon; Yu, Yanni; Luo, Lily et al. (2014) Activated AKT pathway promotes establishment of endometriosis. Endocrinology 155:1921-30
Boele, Joost; Persson, Helena; Shin, Jay W et al. (2014) PAPD5-mediated 3' adenylation and subsequent degradation of miR-21 is disrupted in proliferative disease. Proc Natl Acad Sci U S A 111:11467-72
Dharmaraj, N; Chapela, P J; Morgado, M et al. (2014) Expression of the transmembrane mucins, MUC1, MUC4 and MUC16, in normal endometrium and in endometriosis. Hum Reprod 29:1730-8
Szwarc, Maria M; Kommagani, Ramakrishna; Jeong, Jae-Wook et al. (2014) Perturbing the cellular levels of steroid receptor coactivator-2 impairs murine endometrial function. PLoS One 9:e98664

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