Abstract

Investigators who need to use morphological techniques frequently do not have the facilities in their own laboratories. In addition, project personnel, especially young investigators, often come to the Council without training in these techniques. The Morphology Core provides a number of avenues which enable investigators to produce high quality work involving light and electron microscopy, immunocytochemistry, in situ hybridization, and photography.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
3U54HD013541-20S1
Application #
6301881
Study Section
Project Start
1999-04-01
Project End
2000-03-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
20
Fiscal Year
2000
Total Cost
$238,838
Indirect Cost

  Institution

Name
Population Council
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10017

  Publications

Akingbemi, Benson T; Sottas, Chantal M; Koulova, Anna I et al. (2004) Inhibition of testicular steroidogenesis by the xenoestrogen bisphenol A is associated with reduced pituitary luteinizing hormone secretion and decreased steroidogenic enzyme gene expression in rat Leydig cells. Endocrinology 145:592-603
Lee, Nikki P Y; Cheng, C Yan (2004) Nitric oxide/nitric oxide synthase, spermatogenesis, and tight junction dynamics. Biol Reprod 70:267-76
Dong, Qiang; Salva, Antonio; Sottas, Chantal M et al. (2004) Rapid glucocorticoid mediation of suppressed testosterone biosynthesis in male mice subjected to immobilization stress. J Androl 25:973-81
Mruk, Dolores D; Cheng, C Yan (2004) Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis. Endocr Rev 25:747-806
Walch, Laurence; Clavarino, Emanuela; Morris, Patricia L (2003) Prostaglandin (PG) FP and EP1 receptors mediate PGF2alpha and PGE2 regulation of interleukin-1beta expression in Leydig cell progenitors. Endocrinology 144:1284-91
Siu, Michelle K Y; Lee, Will M; Cheng, C Yan (2003) The interplay of collagen IV, tumor necrosis factor-alpha, gelatinase B (matrix metalloprotease-9), and tissue inhibitor of metalloproteases-1 in the basal lamina regulates Sertoli cell-tight junction dynamics in the rat testis. Endocrinology 144:371-87
Akingbemi, Benson T; Ge, Renshan; Rosenfeld, Cheryl S et al. (2003) Estrogen receptor-alpha gene deficiency enhances androgen biosynthesis in the mouse Leydig cell. Endocrinology 144:84-93
Walch, Laurence; Morris, Patricia L (2002) Cyclooxygenase 2 pathway mediates IL-1beta regulation of IL-1alpha, -1beta, and IL-6 mRNA levels in Leydig cell progenitors. Endocrinology 143:3276-83
Li, Quanxi; Wang, Jun; Armant, D Randall et al. (2002) Calcitonin down-regulates E-cadherin expression in rodent uterine epithelium during implantation. J Biol Chem 277:46447-55
Zhang, Zhifang; Wu, Ai Zhen; Feng, Zong-Ming et al. (2002) Gonadotropins, via cAMP, negatively regulate GATA-1 gene expression in testicular cells. Endocrinology 143:829-36

Showing the most recent 10 out of 22 publications