The training of undergraduates, medical students, predoctoral and postdoctoral students, as well as the general public, organized by the Education and Training Core, is an integral part of this Wellstone Center proposal on """"""""Biomarkers for Therapy of FSHD."""""""" The core's goal is to train the next generation of laboratory and clinician scientists in muscular dystrophy. By targeting students at multiple different levels of training from medical students through postdoctoral fellows, the core aims to increase the number of investigators in the field and to provide them with skills, through mentoring and assistance, to facilitate their transistion to productive, independent careers in muscular dystrophy research. During the previous grant award period, the Education Core has been a particular strength of our Wellstone having initiated a undergraduate student course in muscular dystrophy, trained predoctoral and postdoctoral laboratory students and a clinician scientist, several of whom have gone on to receive independent awards. The Core will continue to provide funding for 2 trainees for all projects involved in this proposal and will continue to involve 12 students from our Wellstone's participating insitutions funded by other mechanisms per year. It will be directed by Drs. Wagner (Core Director), Emerson (PI and Core Co-Director) and Brown (Core Co-Director) who with oversight by the Center Advisory Committee and NIH staff, will work with Center investigators to recruit, appoint, fund and mentor trainees. To enhance training of the students and to educate more broadly all FSHD investigators as well as FSHD patients, the Educational Core will include an annual internal Wellstone retreat, a biennial meeting with a FSH patient group, and an international research conference on FSHD.
FSHD research has gained considerable momentum in the past five years from the creation of this Wellstone as well as support of other collaborating groups. To maintain this momentum and to carry discoveries into the clinic, the number of both laboratory and clinical researchers trained in FSHD needs to grow. The Educational and Training Core of our Wellstone will address this need in the community.
|Sakellariou, Paraskevi; O'Neill, Andrea; Mueller, Amber L et al. (2016) Neuromuscular electrical stimulation promotes development in mice of mature human muscle from immortalized human myoblasts. Skelet Muscle 6:4|
|Chen, Jennifer Cj; King, Oliver D; Zhang, Yuanfan et al. (2016) Morpholino-mediated Knockdown of DUX4 Toward Facioscapulohumeral Muscular Dystrophy Therapeutics. Mol Ther 24:1405-11|
|Henninger, Nils; Bouley, James; Sikoglu, Elif M et al. (2016) Attenuated traumatic axonal injury and improved functional outcome after traumatic brain injury in mice lacking Sarm1. Brain 139:1094-105|
|Jones, Takako I; King, Oliver D; Himeda, Charis L et al. (2015) Individual epigenetic status of the pathogenic D4Z4 macrosatellite correlates with disease in facioscapulohumeral muscular dystrophy. Clin Epigenetics 7:37|
|Homma, Sachiko; Beermann, Mary Lou; Boyce, Frederick M et al. (2015) Expression of FSHD-related DUX4-FL alters proteostasis and induces TDP-43 aggregation. Ann Clin Transl Neurol 2:151-66|
|Moyer, Adam L; Wagner, Kathryn R (2015) Mammalian Mss51 is a skeletal muscle-specific gene modulating cellular metabolism. J Neuromuscul Dis 2:371-385|
|Huh, Yang Hoon; Noh, Minsoo; Burden, Frank R et al. (2015) Sparse feature selection identifies H2A.Z as a novel, pattern-specific biomarker for asymmetrically self-renewing distributed stem cells. Stem Cell Res 14:144-54|
|Lek, Angela; Rahimov, Fedik; Jones, Peter L et al. (2015) Emerging preclinical animal models for FSHD. Trends Mol Med 21:295-306|
|Zhang, Yuanfan; King, Oliver D; Rahimov, Fedik et al. (2014) Human skeletal muscle xenograft as a new preclinical model for muscle disorders. Hum Mol Genet 23:3180-8|
|Jones, Takako I; Yan, Chi; Sapp, Peter C et al. (2014) Identifying diagnostic DNA methylation profiles for facioscapulohumeral muscular dystrophy in blood and saliva using bisulfite sequencing. Clin Epigenetics 6:23|
Showing the most recent 10 out of 23 publications