Here we describe our administrative core and our Translational Pilot project, in response to the RFA. Our proposed U54 SCCPRIR Center is an integrated unit located in the Administrative Suite adjacent to Dr Reijo Pera's office in the Lorry Lokey Institute for Stem Cell Biology and Regenerative Medicine in the School (ISCBRM) of Medicine at Stanford University. The purpose of the Administrative Core is to coordinate functions for our U54 SCCPRIR Center by providing administrative and clerical support for the investigators and technical staff engaged in the Center's research and cores (Figure 1). The general organizational structure is as shown;support for administration is provided by Ms Joie Eckert and Dr Renee Reijo Pera;other personnel are supported on a cost-shared basis with the ISCBRM and the Department of Obstetrics and Gynecology. We note that day-to-day operations of the Administrative Core will involve coordinating the administrative aspects of the award which include: ? Accounting and record keeping, including preparation of requisitions for purchasing, services, supplies, and equipment, processing payment vouchers, and resolving problems between vendors; ? Providing monthly budget statements for each project and core; ? Tracking orders, expenditures, and payments throughout the university and outside suppliers; ? Scheduling quarterly SCCPRIR steering committee meetings and transcribing minutes of these meetings;co-organizing Reproductive Research Day with the Outreach and Education Core; ? Co-organizing and advertising the CRS workshop and journal club meetings for SCCPRIR members;coordinating manuscript and journal publication submissions; ? Compliance with health and safety, radiation safety, use of NIH approved human embryonic stem cell lines, and institutional review for human and animal subjects in medical research; ? Human resources and computer services; ? Coordinating the submission of non-competitive renewals for the U54 center projects and pilot projects and cooperative research initiative applications to the NIH SCCPRIR steering committee; ? Coordinating travel and reimbursements for travel for center director, co-director, and project and core directors, when appropriate, to the SCCPRIR annual research meeting SCCPRIR focus group meetings; ? Coordinate administration of the proposed Translational Pilot Project (see below;if funding is approved)

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54HD068158-02
Application #
8377048
Study Section
Special Emphasis Panel (ZHD1-DSR-L)
Project Start
Project End
Budget Start
2012-04-01
Budget End
2013-03-31
Support Year
2
Fiscal Year
2012
Total Cost
$184,068
Indirect Cost
$72,661
Name
Stanford University
Department
Type
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305
Gustin, Stephanie L F; Wang, Guangwen; Baker, Valerie M et al. (2018) Use of human-derived stem cells to create a novel, in vitro model designed to explore FMR1 CGG repeat instability amongst female premutation carriers. J Assist Reprod Genet :
Woglar, Alexander; Villeneuve, Anne M (2018) Dynamic Architecture of DNA Repair Complexes and the Synaptonemal Complex at Sites of Meiotic Recombination. Cell 173:1678-1691.e16
Karakikes, Ioannis; Termglinchan, Vittavat; Cepeda, Diana A et al. (2017) A Comprehensive TALEN-Based Knockout Library for Generating Human-Induced Pluripotent Stem Cell-Based Models for Cardiovascular Diseases. Circ Res 120:1561-1571
Feng, Yi; Zhu, Shoujun; Antaris, Alexander L et al. (2017) Live imaging of follicle stimulating hormone receptors in gonads and bones using near infrared II fluorophore. Chem Sci 8:3703-3711
Fan, Qianlan; Cheng, Yuan; Chang, Hsun-Ming et al. (2017) Sphingosine-1-phosphate promotes ovarian cancer cell proliferation by disrupting Hippo signaling. Oncotarget 8:27166-27176
Feng, Yi; Cui, Peng; Lu, Xiaowei et al. (2017) CLARITY reveals dynamics of ovarian follicular architecture and vasculature in three-dimensions. Sci Rep 7:44810
Panula, Sarita; Reda, Ahmed; Stukenborg, Jan-Bernd et al. (2016) Over Expression of NANOS3 and DAZL in Human Embryonic Stem Cells. PLoS One 11:e0165268
Kawamura, Kazuhiro; Kawamura, Nanami; Hsueh, Aaron J W (2016) Activation of dormant follicles: a new treatment for premature ovarian failure? Curr Opin Obstet Gynecol 28:217-22
Durruthy-Durruthy, Jens; Sebastiano, Vittorio; Wossidlo, Mark et al. (2016) The primate-specific noncoding RNA HPAT5 regulates pluripotency during human preimplantation development and nuclear reprogramming. Nat Genet 48:44-52
Zhai, Jun; Yao, Guidong; Dong, Fangli et al. (2016) In Vitro Activation of Follicles and Fresh Tissue Auto-transplantation in Primary Ovarian Insufficiency Patients. J Clin Endocrinol Metab 101:4405-4412

Showing the most recent 10 out of 39 publications