The Administrative Core will be responsible for oversight of all administrative aspects of the NYPD-PRC. The administrative core team will facilitate communication amongst all the NYPD-PRC sites, scheduling meetings and seminars and disseminating research information about each project. The Administrative Core team will also negotiate subcontracts and ensure that all sites receive appropriate payment and produce accounting at the end of each budget period. They will keep statistics about site involvement in studies, enrollment across participating sites, AE/SAE reporting to sponsor or FDA (depending on sponsored or investigator-initiated research), internal monitoring and study close-out. 2. Communication between a member of the Administrative Core team and the sites and Cores will occur once every two weeks or more often if necessary. The Administrative Core, with the aid of advice from the core directors, will create and manage the mechanism for soliciting new investigator projects to receive funding from the NYPD-PRC. New projects will be sought from each institution in the consortium. Each project will be reviewed by the Administrative Core and other core directors. These reviewers will critique each project based on scientific merit, feasibility, and necessity for NYPD-PRC cores. The project judged most in keeping with the goals of the consortium will be granted funding for one year, with additional years of funding contingent upon need and scientific progress. The goals of the administrative core are: 1) To organize training and outreach across the participating sites and the BQNN. The network presents a rich environment for young investigators to be exposed to and develop additional research skills and to assist them in progressing to more senior status;2) To provide Cores and investigators reminders of potential funding opportunities through dissemination of FOAs and RFAs electronically to all sites;and 3) To provide regular updates (once every 3 months) or ad hoc on the progress and problems in the consortium. The Outreach Program is imbedded in the Administrative Core with Aranda and Jusko as Co-directors. A key role of the NYPD-PRC is the mentoring of younger investigators, from students to junior faculty. The pool of senior mentors in translational research is deep across collaborating institutions affording unique advantages to traditional brick-and-mortar institutions. By design, the core modules will afford these younger members of the community access to expertise, technology and advice that is not possible otherwise.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54HD071594-04
Application #
8683205
Study Section
Special Emphasis Panel (ZHD1)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
4
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Suny Downstate Medical Center
Department
Type
DUNS #
City
Brooklyn
State
NY
Country
United States
Zip Code
Tu, Chengjian; Li, Jun; Shen, Shichen et al. (2016) Performance Investigation of Proteomic Identification by HCD/CID Fragmentations in Combination with High/Low-Resolution Detectors on a Tribrid, High-Field Orbitrap Instrument. PLoS One 11:e0160160
Beharry, Kay D; Valencia, Gloria B; Lazzaro, Douglas R et al. (2016) Pharmacologic interventions for the prevention and treatment of retinopathy of prematurity. Semin Perinatol 40:189-202
Inayat, Musaddaq; Bany-Mohammed, Fayez; Valencia, Arwin et al. (2015) Antioxidants and Biomarkers of Oxidative Stress in Preterm Infants with Symptomatic Patent Ductus Arteriosus. Am J Perinatol 32:895-904
An, Bo; Zhang, Ming; Johnson, Robert W et al. (2015) Surfactant-aided precipitation/on-pellet-digestion (SOD) procedure provides robust and rapid sample preparation for reproducible, accurate and sensitive LC/MS quantification of therapeutic protein in plasma and tissues. Anal Chem 87:4023-9
Shen, Xiaomeng; Nair, Bindukumar; Mahajan, Supriya D et al. (2015) New Insights into the Disease Progression Control Mechanisms by Comparing Long-Term-Nonprogressors versus Normal-Progressors among HIV-1-Positive Patients Using an Ion Current-Based MS1 Proteomic Profiling. J Proteome Res 14:5225-39
Jivabhai Patel, Shamin; Bany-Mohammed, Fayez; McNally, Lois et al. (2015) Exogenous Superoxide Dismutase Mimetic Without Scavenging H2O2 Causes Photoreceptor Damage in a Rat Model for Oxygen-Induced Retinopathy. Invest Ophthalmol Vis Sci 56:1665-77
Tu, Chengjian; Beharry, Kay D; Shen, Xiaomeng et al. (2015) Proteomic profiling of the retinas in a neonatal rat model of oxygen-induced retinopathy with a reproducible ion-current-based MS1 approach. J Proteome Res 14:2109-20
Tu, Chengjian; Sheng, Quanhu; Li, Jun et al. (2015) Optimization of Search Engines and Postprocessing Approaches to Maximize Peptide and Protein Identification for High-Resolution Mass Data. J Proteome Res 14:4662-73
Kamisoglu, Kubra; Sukumaran, Siddharth; Nouri-Nigjeh, Eslam et al. (2015) Tandem analysis of transcriptome and proteome changes after a single dose of corticosteroid: a systems approach to liver function in pharmacogenomics. OMICS 19:80-91
Lott, Kaylen; Mukhopadhyay, Shreya; Li, Jun et al. (2015) Arginine methylation of DRBD18 differentially impacts its opposing effects on the trypanosome transcriptome. Nucleic Acids Res 43:5501-23

Showing the most recent 10 out of 32 publications