Agency
National Institute of Health (NIH)
Institute
National Human Genome Research Institute (NHGRI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54HG005031-05
Application #
8379496
Study Section
Special Emphasis Panel (ZRG1-IFCN-K)
Project Start
Project End
Budget Start
2012-06-01
Budget End
2013-05-31
Support Year
5
Fiscal Year
2012
Total Cost
$2,109,041
Indirect Cost
$674,319
Name
University of Kansas Lawrence
Department
Type
DUNS #
076248616
City
Lawrence
State
KS
Country
United States
Zip Code
66045
Hackler, Amber; Patrick, Stephen L; Kahney, Elizabeth W et al. (2017) Antiparasitic lethality of sulfonamidebenzamides in kinetoplastids. Bioorg Med Chem Lett 27:755-758
Chattopadhyay, Debasish; Swingle, Mark R; Salter, Edward A et al. (2016) Crystal structures and mutagenesis of PPP-family ser/thr protein phosphatases elucidate the selectivity of cantharidin and novel norcantharidin-based inhibitors of PP5C. Biochem Pharmacol 109:14-26
Skarsfeldt, Mark A; Jepps, Thomas A; Bomholtz, Sofia H et al. (2016) pH-dependent inhibition of K?P3.1 prolongs atrial refractoriness in whole hearts. Pflugers Arch 468:643-54
Aflaki, Elma; Borger, Daniel K; Moaven, Nima et al. (2016) A New Glucocerebrosidase Chaperone Reduces ?-Synuclein and Glycolipid Levels in iPSC-Derived Dopaminergic Neurons from Patients with Gaucher Disease and Parkinsonism. J Neurosci 36:7441-52
Chung, Dong-Hoon; Golden, Jennifer E; Adcock, Robert S et al. (2016) Discovery of a Broad-Spectrum Antiviral Compound That Inhibits Pyrimidine Biosynthesis and Establishes a Type 1 Interferon-Independent Antiviral State. Antimicrob Agents Chemother 60:4552-62
Gui, Lin; Zhang, Xiaoyi; Li, Kelin et al. (2016) Evaluating p97 Inhibitor Analogues for Potency against p97-p37 and p97-Npl4-Ufd1 Complexes. ChemMedChem 11:953-7
Gold, Ben; Smith, Robert; Nguyen, Quyen et al. (2016) Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis. J Med Chem 59:6027-44
Roy, Sudeshna; Ĺ ileikyt?, Justina; Neuenswander, Benjamin et al. (2016) N-Phenylbenzamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore. ChemMedChem 11:283-8
Arshad, Mehreen; Goller, Carlos C; Pilla, Danielle et al. (2016) Threading the Needle: Small-Molecule Targeting of a Xenobiotic Receptor to Ablate Escherichia coli Polysaccharide Capsule Expression Without Altering Antibiotic Resistance. J Infect Dis 213:1330-9
Schroeder, Chad E; Neuenswander, Sarah A; Yao, Tuanli et al. (2016) One-pot, regiospecific assembly of (E)-benzamidines from ?- and ?-amino acids via an intramolecular aminoquinazolinone rearrangement. Org Biomol Chem 14:3950-5

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