UNIT 2. HIGH-THROUGHPUT SCREENING The HTS Unit has extensive expertise in performing biochemical and cell-based assays and exceeded its commitment to the MLSCN, thus far uploading >3.4 million data points into PubChem from 36 screening campaigns using the NIH library, plus another 3 screening campaigns using Burnham's in-house library, when the NIH library failed to yield tractable hits (total 39). We describe progress to date and plans to perform a minimum of 25 screens per year using the NIH library of 300K-500K compounds during the MLPCN Phase.

Agency
National Institute of Health (NIH)
Institute
National Human Genome Research Institute (NHGRI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54HG005033-05
Application #
8379687
Study Section
Special Emphasis Panel (ZRG1-IFCN-K)
Project Start
Project End
2014-05-31
Budget Start
2012-06-01
Budget End
2013-05-31
Support Year
5
Fiscal Year
2012
Total Cost
$638,236
Indirect Cost
$304,081
Name
Sanford-Burnham Medical Research Institute
Department
Type
DUNS #
020520466
City
La Jolla
State
CA
Country
United States
Zip Code
92037
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