Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Human Genome Research Institute (NHGRI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
1U54HG005034-01
Application #
7695386
Study Section
Special Emphasis Panel (ZRG1-IFCN-K (52))
Project Start
2008-09-01
Project End
2014-05-31
Budget Start
2008-09-01
Budget End
2009-05-31
Support Year
1
Fiscal Year
2008
Total Cost
$689,455
Indirect Cost

  Institution

Name
Southern Research Institute
Department
Type
DUNS #
006900526
City
Birmingham
State
AL
Country
United States
Zip Code
35205

  Publications

Rasmussen, Lynn; White, E Lucile; Bostwick, James R (2016) Acoustic Droplet Ejection Applications for High-Throughput Screening of Infectious Agents. J Lab Autom 21:188-97
Rasmussen, Lynn; Tigabu, Bersabeh; White, E Lucile et al. (2015) Adapting high-throughput screening methods and assays for biocontainment laboratories. Assay Drug Dev Technol 13:44-54
Schreiber, Stuart L; Kotz, Joanne D; Li, Min et al. (2015) Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes. Cell 161:1252-65
Atkins, Colm; Evans, Carrie W; Nordin, Brian et al. (2014) Global Human-Kinase Screening Identifies Therapeutic Host Targets against Influenza. J Biomol Screen 19:936-46
Matharu, Daljit S; Flaherty, Daniel P; Simpson, Denise S et al. (2014) Optimization of potent and selective quinazolinediones: inhibitors of respiratory syncytial virus that block RNA-dependent RNA-polymerase complex activity. J Med Chem 57:10314-28
Schroeder, Chad E; Yao, Tuanli; Sotsky, Julie et al. (2014) Development of (E)-2-((1,4-dimethylpiperazin-2-ylidene)amino)-5-nitro-N-phenylbenzamide, ML336: Novel 2-amidinophenylbenzamides as potent inhibitors of venezuelan equine encephalitis virus. J Med Chem 57:8608-21
Wang, Hongxia; Silva, Anisia J; Rasmussen, Lynn et al. (2013) A highly specific cell-based high-throughput screening assay for ligands of cyclic adenosine monophosphate receptor protein in gram-negative bacteria. Assay Drug Dev Technol 11:382-7
Wang, Hongxia; Zhang, Li; Silva, Anisia J et al. (2013) A quinazoline-2,4-diamino analog suppresses Vibrio cholerae flagellar motility by interacting with motor protein PomB and induces envelope stress. Antimicrob Agents Chemother 57:3950-9
Chung, Dong-Hoon; Moore, Blake P; Matharu, Daljit S et al. (2013) A cell based high-throughput screening approach for the discovery of new inhibitors of respiratory syncytial virus. Virol J 10:19
Atkins, Colm; Evans, Carrie W; White, E Lucile et al. (2012) Screening methods for influenza antiviral drug discovery. Expert Opin Drug Discov 7:429-38

Showing the most recent 10 out of 17 publications