The Puerto Rico Clinical and Translational Research Consortium (PRCTRC) is an innovative model of collaboration, bringing together and leveraging the intellectual and physical resources of three major medical and health science centers in Puerto Rico: The University of Puerto Rico Medical Sciences Campus (UPRMSC), the Universidad del Caribe Central (UCC), and the Ponce School of Medicine &Health Sciences (PSM&HS) to address and reduce health disparities that most impact Hispanic populations. The mission is to serve as a vital and catalytic element in the efforts to understand, define, and address health disparities in Hispanic populations. Our efforts are guided by four strategic goals: 1) Facilitate the generation and translation of knowledge from the bench into the community by establishing a centralized program focused on reducing health disparities among Hispanic populations;2) Enhance and support existing training and mentoring programs to increase the number of new minority investigators in Clinical and Translational Research;3) Encourage collaborations among basic, clinical, and social scientists and community networks and health programs;and 4) Enhance and integrate existing infrastructure for clinical and translational research across Puerto Rico to support and expand Clinical and Translational Research in health disparities The PRCTRC has fostered a synergistic environment that supports research across the clinical and translational research continuum, with an emphasis on four disease states that post the greatest threats to Hispanic health: HIV/AIDS, neurological diseases, cardiovascular and metabolic diseases, and cancer. The PRCTRC provides this integrated infrastructure to investigators through nine Cores: Regulatory Knowledge and Support, Research Design and Biostatistics, clinical Research Resources and Facilities, Technology Resources for Core Laboratories, Biomedical Informatics, Collaborations and Partnerships, Professional Development, Clinical and Translational Pilot Project Program, and Community-based Research. Oversight is provided by an Administrative Core and formative and summative evaluation is provided by an Evaluation Core.
Health disparities among underrepresented minorities constitute an important public health problem. This project proposes to generate important knowledge about the underlying causes and the most effective methods to reduce these health disparities among Hispanics. This project will also increase the participation of underrepresented minority investigators working on this problem.
|Rodriguez-Velazquez, Ariel; Velez, Rosa; Lafontaine, Jean Carlo et al. (2018) Prevalence of breast and ovarian cancer subtypes in Hispanic populations from Puerto Rico. BMC Cancer 18:1177|
|Jordán-González, Patricia; Shum, Lee Ming; González-Sepúlveda, Lorena et al. (2018) Clinical correlates and outcomes in a group of Puerto Ricans with systemic lupus erythematosus hospitalized due to severe infections. SAGE Open Med 6:2050312118778385|
|Brau, Ricardo H; Acevedo-Salas, Yaritza; Giovannetti, Katya (2018) Epidemiological Trends of Traumatic Brain and Spinal Cord Injury in Puerto Rico from November 10th, 2006, through May 24th, 2011. P R Health Sci J 37:67-77|
|Ortiz, Ana Patricia; González, Daisy; Vivaldi-Oliver, José et al. (2018) Periodontitis and oral human papillomavirus infection among Hispanic adults. Papillomavirus Res 5:128-133|
|Pérez-Caraballo, Aixa M; Suarez, Erick; Unger, Elizabeth R et al. (2018) Seroprevalence of Human Papillomavirus (HPV) Type 6, 11, 16, 18, by Anatomic Site of HPV Infection, in Women Aged 16-64 Years living in the Metropolitan Area of San Juan, Puerto Rico. P R Health Sci J 37:26-31|
|Diaz, Clemente; Lin, Leyi; Martinez, Luis J et al. (2018) Phase I Randomized Study of a Tetravalent Dengue Purified Inactivated Vaccine in Healthy Adults from Puerto Rico. Am J Trop Med Hyg 98:1435-1443|
|Grover, Surbhi; Desir, Fidel; Jing, Yuezhou et al. (2018) Reduced Cancer Survival Among Adults With HIV and AIDS-Defining Illnesses Despite No Difference in Cancer Stage at Diagnosis. J Acquir Immune Defic Syndr 79:421-429|
|González De León, Joenice; González Méndez, Ricardo; Cadilla, Carmen L et al. (2018) Identification of Immunoglobulin E-Binding Proteins of the Xerophilic Fungus Aspergillus penicillioides Crude Mycelial Mat Extract and Serological Reactivity Assessment in Subjects with Different Allergen Reactivity Profiles. Int Arch Allergy Immunol 175:147-159|
|Preston, Alan M; Rodríguez-Orengo, José; González-Sepúlveda, Lorena et al. (2018) Effect of Housing Type on 25 OH Vitamin D in Serum of Rhesus Monkeys. P R Health Sci J 37:124-127|
|Jusino, Shirley; Fernández-Padín, Fabiola M; Saavedra, Harold I (2018) Centrosome aberrations and chromosome instability contribute to tumorigenesis and intra-tumor heterogeneity. J Cancer Metastasis Treat 4:|
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