The vision ofthe Charles Drew University of Medicine and Science (CDU) Research Enterprise is to be a leading national resource for conducting clinical and translational research that produces high-quality, costeffective and culturally relevant solutions that improve health and wellness in minority and poor populations. By promoting strategies that create synergy in research teams and between investigators and the community, CDU will create novel best practice solutions to transform the health of underserved communities that can be used as innovative models throughout the nation and the world. CDU submits this application in response to the NIH Program Announcement (PAR-08-262) to implement the consolidation of the Comprehensive Center for Health Disparities (CCHD) and Clinical Research Center (CRC) into Accelerating excellence In Science (AXIS). AXIS will be the catalyst to implement the CDU research strategic plan and will become the integrated """"""""home"""""""" for clinical and translational research. AXIS will house experienced and dedicated leadership;a myriad of clinical and translational, community, training, and technology resources;and excellent research consultation services. As its cornerstone, AXIS wi|l have multiand interdisciplinary collaborations between CDU investigators and community partners. These team science activities will be supported by CDU biomedical informatics resources, and other innovative research tools and information technologies (detailed below) aligned in an integrated manner to create a vibrant center for clinical and translational science. The overall purpose of AXIS is to better position CDU for conducting clinical and translational research, especially research that is focused on health disparities. The goals are to: Goal 1: Transform the CDU research enterprise from traditional basic and clinical research domains into a highly integrated clinical and translational research environment by reorganizing research administration, centralizing and enhancing physical and intellectual resources, and promoting participation in the RCMI Translational Research Network (RTRN) and Clinical and Translational Science Institutes (CTSI). Goal 2: Develop a unique model for community, multi-disciplinary, and/or multi-institutional partnerships that ensures that clinical and translational research yields high-quality, cost-effective health outcomes Goal 3: Implement innovative translational research training and career development activities at CDU and in partnership with RTRN that recognize that the interdependence of basic science, clinical discovery, and patient-oriented research will accelerate improved patient outcomes.

National Institute of Health (NIH)
National Institute on Minority Health and Health Disparities (NIMHD)
Specialized Center--Cooperative Agreements (U54)
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Special Emphasis Panel (ZRR1-RI-8 (01))
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Mcclure, Shelia A
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Charles R. Drew University of Medicine & Science
Other Domestic Higher Education
Los Angeles
United States
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Madadi, Firooz; Madadi, Firoozeh; Maleki, Arash et al. (2016) A new method for tibial torsion measurement by computerized tomography. J Orthop 13:43-7
Bazargan, Mohsen; Yazdanshenas, Hamed; Han, Shelley et al. (2016) Inappropriate Medication Use Among Underserved Elderly African Americans. J Aging Health 28:118-38
Wu, Yanyuan; Sarkissyan, Marianna; Vadgama, Jaydutt V (2016) Epithelial-Mesenchymal Transition and Breast Cancer. J Clin Med 5:
Yazdanshenas, Hamed; Bazargan, Mohsen; Smith, James et al. (2016) Pain Treatment of Underserved Older African Americans. J Am Geriatr Soc 64:2116-2121
Yazdanshenas, Hamed; Washington 4th, Eleby R; Shamie, Arya Nick et al. (2016) Senior Managed Care System for Hip Fracture in the United States. Clin Orthop Surg 8:19-28
Schwartzman, Monica; Reginensi, Antoine; Wong, Jenny S et al. (2016) Podocyte-Specific Deletion of Yes-Associated Protein Causes FSGS and Progressive Renal Failure. J Am Soc Nephrol 27:216-26
Harris, Kindred K; Zopey, Mohan; Friedman, Theodore C (2016) Metabolic effects of smoking cessation. Nat Rev Endocrinol 12:299-308
Gelfand, Robert; Vernet, Dolores; Bruhn, Kevin et al. (2016) Long-term exposure of MCF-12A normal human breast epithelial cells to ethanol induces epithelial mesenchymal transition and oncogenic features. Int J Oncol 48:2399-414
Del Pino, Homero E; Jones, Loretta; Forge, Nell et al. (2016) Integrating Community Expertise into the Academy: South Los Angeles' Community-Academic Model for Partnered Research. Prog Community Health Partnersh 10:329-38
Bazargan, Mohsen; Yazdanshenas, Hamed; Gordon, David et al. (2016) Pain in Community-Dwelling Elderly African Americans. J Aging Health 28:403-25

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