We propose a SNRP at the University of Texas at San Antonio. UTSA is a young institution with a commitment to rapid growth in graduate training and research in Neuroscience, and an emphasis on quantitative and computational research. In the past 3 years the Department of Biology at UTSA has hired 6 promising young tenure-track neurobiology faculty from among the best labs in the country to represent a cross-section of neuroscience disciplines and advance Neuroscience within our institution. Most of these new scientists are assistant professors, who have never previously held faculty positions. In the upcoming 5 years we are committed to hiring 5 additional tenure-track Neuroscientists with research interests in topics fundamental to the understanding of nervous system function and disorders, including neural control of movement, central pattern generation, structural plasticity in the adult nervous system, ion channel structure and function, and behavioral genetics. During this time of rapid growth of our Neuroscience group, we envision the SNRP functioning as the center of the Neuroscience community at UTSA. The program will develop a community of UTSA researchers and their collaborators at other institutions. It will support a shared research infrastructure tailored to Neurobiology research by providing resources and expertise in the design, collection and quantitative analysis of numerical and image data. We will offer training and leadership to foster the development of our promising new faculty. We will provide critical evaluation, advice and support for their collaborative pilot research, by providing guidance and direct help in the administrative and management issues that arise in establishing their new laboratories. The SNRP leadership will also act as an advocate for their interests at the college and university levels as they establish their independent research programs and develop into productive managers, scientists and scholars. A second focus of the SNRP will be to provide training opportunities that supplement the Neurobiology Ph.D program, including seminars, symposia, and year-long competitive training fellowships for students interested in pursuing advanced mathematical or statistical studies while in our program.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54NS060658-05
Application #
8320248
Study Section
Special Emphasis Panel (ZNS1-SRB-P (40))
Program Officer
Gordon, Alfred W
Project Start
2008-08-15
Project End
2014-07-31
Budget Start
2012-08-01
Budget End
2014-07-31
Support Year
5
Fiscal Year
2012
Total Cost
$1,062,069
Indirect Cost
$263,297
Name
University of Texas Health Science Center San Antonio
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
800189185
City
San Antonio
State
TX
Country
United States
Zip Code
78249
Gaval-Cruz, Meriem; Goertz, Richard B; Puttick, Daniel J et al. (2014) Chronic loss of noradrenergic tone produces ?-arrestin2-mediated cocaine hypersensitivity and alters cellular D2 responses in the nucleus accumbens. Addict Biol :
Chen, Yiju; Moon, Anne M; Gaufo, Gary O (2012) Influence of mesodermal Fgf8 on the differentiation of neural crest-derived postganglionic neurons. Dev Biol 361:125-36
Takano-Maruyama, Masumi; Chen, Yiju; Gaufo, Gary O (2012) Differential contribution of Neurog1 and Neurog2 on the formation of cranial ganglia along the anterior-posterior axis. Dev Dyn 241:229-41
Chen, Yiju; Takano-Maruyama, Masumi; Fritzsch, Bernd et al. (2012) Hoxb1 controls anteroposterior identity of vestibular projection neurons. PLoS One 7:e34762
Lobb, Collin J; Wilson, Charles J; Paladini, Carlos A (2011) High-frequency, short-latency disinhibition bursting of midbrain dopaminergic neurons. J Neurophysiol 105:2501-11
Morikawa, H; Paladini, C A (2011) Dynamic regulation of midbrain dopamine neuron activity: intrinsic, synaptic, and plasticity mechanisms. Neuroscience 198:95-111
Ko, Daijin; Windle, Brad (2011) Enriching for correct prediction of biological processes using a combination of diverse classifiers. BMC Bioinformatics 12:189
Lobb, Collin J; Wilson, Charles J; Paladini, Carlos A (2010) A dynamic role for GABA receptors on the firing pattern of midbrain dopaminergic neurons. J Neurophysiol 104:403-13
Moorman, David E; Aston-Jones, Gary (2010) Orexin/hypocretin modulates response of ventral tegmental dopamine neurons to prefrontal activation: diurnal influences. J Neurosci 30:15585-99
Lobb, Collin J; Paladini, Carlos A (2010) Application of a NMDA receptor conductance in rat midbrain dopaminergic neurons using the dynamic clamp technique. J Vis Exp :

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