The goal of the BVMC Pilot/Demonstration Projects Program (PPP) is to fund promising projects that take advantage of new clinical research opportunities in rare diseases. Typically, these projects demonstrate feasibility and generate proof-of-concept data for future grant funding and clinical studies. These projects will have potential for high impact to the relevant projects in the BVMC. We will support a minimum of 3 or a maximum of 5 pilot projects (one per year) for the duration of the grant.
Aim : To select, fund, and oversee high-quality pilot project proposals relevant for BVMC projects. The Administrative Unit will manage pilot projects, but the BVMC Executive Steering Committee will formulate decisions regarding project funding, taking into consideration clinical research potential in rare diseases, thematic relationship to the aims and scope of the BVMC, quality of the proposal, feasibility in projected time frame, and ability to support promising junior investigators. The Genetics, Statistics and Analysis Core will provide experimental design, genetic and statistical analysis support as needed.

Agency
National Institute of Health (NIH)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
2U54NS065705-06
Application #
8913455
Study Section
Special Emphasis Panel (ZTR1)
Program Officer
Moy, Claudia S
Project Start
Project End
Budget Start
Budget End
Support Year
6
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Type
DUNS #
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Choquet, Hélène; Nelson, Jeffrey; Pawlikowska, Ludmila et al. (2014) Association of cardiovascular risk factors with disease severity in cerebral cavernous malformation type 1 subjects with the common Hispanic mutation. Cerebrovasc Dis 37:57-63
Reidy, Teressa Garcia; Suskauer, Stacy J; Bachur, Cathy D et al. (2014) Preliminary reliability and validity of a battery for assessing functional skills in children with Sturge-Weber syndrome. Childs Nerv Syst 30:2027-36
Cheng, Kyle H Y; Mariampillai, Adrian; Lee, Kenneth K C et al. (2014) Histogram flow mapping with optical coherence tomography for in vivo skin angiography of hereditary hemorrhagic telangiectasia. J Biomed Opt 19:086015
Lance, Eboni I; Sreenivasan, Aditya K; Zabel, T Andrew et al. (2013) Aspirin use in Sturge-Weber syndrome: side effects and clinical outcomes. J Child Neurol 28:213-8
Sreenivasan, Aditya K; Bachur, Catherine D; Lanier, Kira E et al. (2013) Urine vascular biomarkers in Sturge-Weber syndrome. Vasc Med 18:122-8
Lopez, Jonathan; Yeom, Kristen W; Comi, Anne et al. (2013) Case report of subdural hematoma in a patient with Sturge-Weber syndrome and literature review: questions and implications for therapy. J Child Neurol 28:672-5
Siddique, Laila; Sreenivasan, Aditya; Comi, Anne M et al. (2013) Importance of utilizing a sensitive free thyroxine assay in Sturge-Weber syndrome. J Child Neurol 28:269-74
Arora, Karun S; Quigley, Harry A; Comi, Anne M et al. (2013) Increased choroidal thickness in patients with Sturge-Weber syndrome. JAMA Ophthalmol 131:1216-9
Shirley, Matthew D; Tang, Hao; Gallione, Carol J et al. (2013) Sturge-Weber syndrome and port-wine stains caused by somatic mutation in GNAQ. N Engl J Med 368:1971-9
Lo, Warren; Marchuk, Douglas A; Ball, Karen L et al. (2012) Updates and future horizons on the understanding, diagnosis, and treatment of Sturge-Weber syndrome brain involvement. Dev Med Child Neurol 54:214-23

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