The goal of the BVMC Pilot/Demonstration Projects Program (PPP) is to fund promising projects that take advantage of new clinical research opportunities in rare diseases. Typically, these projects demonstrate feasibility and generate proof-of-concept data for future grant funding and clinical studies. These projects will have potential for high impact to the relevant projects in the BVMC. We will support a minimum of 3 or a maximum of 5 pilot projects (one per year) for the duration of the grant.
Aim : To select, fund, and oversee high-quality pilot project proposals relevant for BVMC projects. The Administrative Unit will manage pilot projects, but the BVMC Executive Steering Committee will formulate decisions regarding project funding, taking into consideration clinical research potential in rare diseases, thematic relationship to the aims and scope of the BVMC, quality of the proposal, feasibility in projected time frame, and ability to support promising junior investigators. The Genetics, Statistics and Analysis Core will provide experimental design, genetic and statistical analysis support as needed.
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|Kavanaugh, Brian; Sreenivasan, Aditya; Bachur, Catherine et al. (2016) [Formula: see text]Intellectual and adaptive functioning in Sturge-Weber Syndrome. Child Neuropsychol 22:635-48|
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|Kaplan, Emma H; Kossoff, Eric H; Bachur, Catherine D et al. (2016) Anticonvulsant Efficacy in Sturge-Weber Syndrome. Pediatr Neurol 58:31-6|
|Krings, T; Kim, H; Power, S et al. (2015) Neurovascular manifestations in hereditary hemorrhagic telangiectasia: imaging features and genotype-phenotype correlations. AJNR Am J Neuroradiol 36:863-70|
|Golden, Michael; Saeidi, Saba; Liem, Benny et al. (2015) Sensitivity of patients with familial cerebral cavernous malformations to therapeutic radiation. J Med Imaging Radiat Oncol 59:134-6|
|Choquet, H; Pawlikowska, L; Lawton, M T et al. (2015) Genetics of cerebral cavernous malformations: current status and future prospects. J Neurosurg Sci 59:211-20|
|Comi, Anne M (2015) Sturge-Weber syndrome. Handb Clin Neurol 132:157-68|
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