The overarching goal of Core C (""""""""Biomarker Collection &Analysis Core"""""""") is to provide a centralized resource where SPIRP Center faculty and affiliates can go to obtain high-quality data collection and data management advice and assistance to support optimal research on stroke disparities. Core C builds on a foundation of extensive prior experience in biomarker (and other data) collecfion, processing, management and analysis, and leverages expertise in engagement with communities that typify health disparity populations in the most diverse county within the United States. Core C faculty have previously developed similar, highly successful research operafions cores and bring an extensive and successful track record of executing communitybased observational and intervention research. Core C will leverage this prior experience and expertise to accomplish the following Specific Aims: (1). Support biomarker data collection for the two intervention trials, Projects 1 &3, including facilitating development and implementation of all data collecfion and data processing protocols for planned biomarkers, and collaborating with Core A to integrate proposed Core C data collection and data management acfivifies within the SPIRP's global IT and web site infrastructure; (2) Provide expert consulting for biomarker data analysis for Projects 1, 2 and 3, drawing on expertise in analysis of biomarker data to assist all proposed SPIRP projects with review of raw data, needed data transformations, implementation of analyses and interpretafion of results; (3). Collaborate with Core B to provide training and education for junior invesfigators and community stakeholders, contributing expertise to the production of materials on topics related to collection and interpretation of biomarkers;^ (4). Establish metrics to assess progress of Specific Aims 1, 2 &3, following a pre-estaBlished timeline for define benchmarks to measure adherence to Core goals, assess operational efficiency, and generate strategies for continuous improvement. f The overarching goal of Core C is to contribute to the success of the overall SPIRP Center by advising and assisfing SPIRP researchers in optimizing data collection and data management systems for their respective studies to ensure the highest quality data for addressing critical research questions.

Public Health Relevance

The goal of Core C (Biomarker Collection &Analysis Core) is to support and enhance the sucdess of the overall SPIRP Center by providing a central resource for advice and assistance to SPIRP researchers in optimizing data collection and data management systems for their respective studies to ensure the highest quality data for addressing crifical research questions.

National Institute of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Specialized Center--Cooperative Agreements (U54)
Project #
Application #
Study Section
Special Emphasis Panel (ZNS1-SRB-N (02))
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of California Los Angeles
Los Angeles
United States
Zip Code
Choi, Sarah E; Kwon, Ivy; Chang, Emiley et al. (2016) Developing a culturally tailored stroke prevention walking programme for Korean immigrant seniors: a focus group study. Int J Older People Nurs 11:255-265
Bharmal, Nazleen; Lucas-Wright, Anna Aziza; Vassar, Stefanie D et al. (2016) A Community Engagement Symposium to Prevent and Improve Stroke Outcomes in Diverse Communities. Prog Community Health Partnersh 10:149-58
Kwon, Ivy; Bharmal, Nazleen; Choi, Sarah et al. (2016) Older Ethnic Minority Women's Perceptions of Stroke Prevention and Walking. Womens Health Issues 26:80-6
Mensah, George A; Sacco, Ralph L; Vickrey, Barbara G et al. (2015) From Data to Action: Neuroepidemiology Informs Implementation Research for Global Stroke Prevention and Treatment. Neuroepidemiology 45:221-9
Roumie, Christianne L; Zillich, Alan J; Bravata, Dawn M et al. (2015) Hypertension treatment intensification among stroke survivors with uncontrolled blood pressure. Stroke 46:465-70
Kwon, Ivy; Choi, Sarah; Mittman, Brian et al. (2015) Study protocol of ""Worth the Walk"": a randomized controlled trial of a stroke risk reduction walking intervention among racial/ethnic minority older adults with hypertension in community senior centers. BMC Neurol 15:91
Lin, Michelle P; Ovbiagele, Bruce; Markovic, Daniela et al. (2015) ""Life's Simple 7"" and Long-Term Mortality After Stroke. J Am Heart Assoc 4:
Moura, Lidia M V R; Mendez, Diego Yacaman; Jesus, Jonathan De et al. (2015) Association of adherence to epilepsy quality standards with seizure control. Epilepsy Res 117:35-41
Vickrey, Barbara G (2015) Comment: The changing practice of neurology and a look to the future. Neurology 84:2090
Hamid, Hamada; Blackmon, Karen; Cong, Xiangyu et al. (2014) Mood, anxiety, and incomplete seizure control affect quality of life after epilepsy surgery. Neurology 82:887-94

Showing the most recent 10 out of 27 publications