To assure the effectiveness and success of the MSM SNRP in its programmatic goals, the program will undergo dual evaluation during the term of the award by the EAC and by professional Program Evaluators (PE). With guidance from the EAC, PE will support assessment of the Research Program and Enrichment Program. This Evaluation Plan describes the objectives of the SNRP Program and lists defined metrics developed by the SNRP investigators in concert with the EAC and PE. The Program Evaluators do not serve in an advisory role to the SNRP Program. The role of the evaluation team is to determine whether the components of the SNRP program met the evaluation metrics set forth in this application. The program evaluation by the PE will depend on a rigorous evaluation that includes both internal and external evaluation components with clearly delineated, yet complimentary approaches that comprehensively evaluate each targeted objectives. Assessment will be based on monitoring achievement of evaluation indicators detailed in this section. The PE will prepare an annual report that will be submitted to both the EAC and the NINDS who will determine the progress of the SNRP and make recommendation for adjustments to the program as needed.

National Institute of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Specialized Center--Cooperative Agreements (U54)
Project #
Application #
Study Section
Special Emphasis Panel (ZNS1-SRB-N (03))
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Morehouse School of Medicine
United States
Zip Code
Leng, Tian-Dong; Li, Ming-Hua; Shen, Jian-Feng et al. (2015) Suppression of TRPM7 inhibits proliferation, migration, and invasion of malignant human glioma cells. CNS Neurosci Ther 21:252-61
Harms, Jonathan E; Benveniste, Morris; Kessler, Markus et al. (2014) A charge-inverting mutation in the "linker" region of ?-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors alters agonist binding and gating kinetics independently of allosteric modulators. J Biol Chem 289:10702-14
O'Bryant, Zaven; Vann, Kiara T; Xiong, Zhi-Gang (2014) Translational strategies for neuroprotection in ischemic stroke--focusing on acid-sensing ion channel 1a. Transl Stroke Res 5:59-68
Leng, Tiandong; Shi, Yejie; Xiong, Zhi-Gang et al. (2014) Proton-sensitive cation channels and ion exchangers in ischemic brain injury: new therapeutic targets for stroke? Prog Neurobiol 115:189-209
Li, Ming-Hua; Liu, Selina Qiuying; Inoue, Koichi et al. (2014) Acid-sensing ion channels in mouse olfactory bulb M/T neurons. J Gen Physiol 143:719-31
McMahon, Douglas G; Iuvone, P Michael; Tosini, Gianluca (2014) Circadian organization of the mammalian retina: from gene regulation to physiology and diseases. Prog Retin Eye Res 39:58-76
Inagaki, Akira; Frank, C Andrew; Usachev, Yuriy M et al. (2014) Pharmacological correction of gating defects in the voltage-gated Ca(v)2.1 Ca²? channel due to a familial hemiplegic migraine mutation. Neuron 81:91-102
Weeks, Autumn M; Harms, Jonathan E; Partin, Kathryn M et al. (2014) Functional insight into development of positive allosteric modulators of AMPA receptors. Neuropharmacology 85:57-66
Hiragaki, Susumu; Baba, Kenkichi; Coulson, Elise et al. (2014) Melatonin signaling modulates clock genes expression in the mouse retina. PLoS One 9:e106819